Diseases involve complex modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, new biological knowledge about a disease can be extracted from these prof...
International journal of environmental research and public health
Apr 4, 2020
The main aim of this study is to assess groundwater potential of the DakNong province, Vietnam, using an advanced ensemble machine learning model (RABANN) that integrates Artificial Neural Networks (ANN) with RealAdaBoost (RAB) ensemble technique. F...
PURPOSE: We sought to assess the performance of deep learning approaches for differentiating nonglaucomatous optic neuropathy with disc pallor (NGON) vs glaucomatous optic neuropathy (GON) on color fundus photographs by the use of image recognition.
Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted from pre-tr...
Physical and engineering sciences in medicine
Apr 1, 2020
An approach is proposed for the detection of chronic heart disorders from the electrocardiogram (ECG) signals. It utilizes an intelligent event-driven ECG signal acquisition system to achieve a real-time compression and effective signal processing an...
Neural networks : the official journal of the International Neural Network Society
Apr 1, 2020
Convolutional neural networks (CNNs), a popular type of deep neural network, have been actively applied to image recognition, object detection, object localization, semantic segmentation, and object instance segmentation. Accordingly, the applicabili...
Advances in genome sequencing have led to a tremendous increase in the discovery of novel missense variants, but evidence for determining clinical significance can be limited or conflicting. Here, we present Learning from Evidence to Assess Pathogeni...
The Journal of investigative dermatology
Mar 31, 2020
Although deep learning algorithms have demonstrated expert-level performance, previous efforts were mostly binary classifications of limited disorders. We trained an algorithm with 220,680 images of 174 disorders and validated it using Edinburgh (1,3...
OBJECTIVES: We develop and validate a radiomics model based on multiparametric magnetic resonance imaging (MRI) in the classification of the pulmonary lesion and identify optimal machine learning methods.
Computational and mathematical methods in medicine
Mar 28, 2020
Prediction of DNA-binding proteins (DBPs) has become a popular research topic in protein science due to its crucial role in all aspects of biological activities. Even though considerable efforts have been devoted to developing powerful computational ...
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