AIMC Topic:
ROC Curve

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Decision Support System for Seizure Onset Zone Localization Based on Channel Ranking and High-Frequency EEG Activity.

IEEE journal of biomedical and health informatics
Interictal high-frequency oscillations (HFO) are a promising biomarker that can help define the seizure onset zone (SOZ) and predict the surgical outcome after the epilepsy surgery. The utility of HFO in planning the surgery, though, is unclear. Reas...

Methodological variations in lagged regression for detecting physiologic drug effects in EHR data.

Journal of biomedical informatics
We studied how lagged linear regression can be used to detect the physiologic effects of drugs from data in the electronic health record (EHR). We systematically examined the effect of methodological variations ((i) time series construction, (ii) tem...

Quantitative structure-activity relationship analysis using deep learning based on a novel molecular image input technique.

Bioorganic & medicinal chemistry letters
Quantitative structure-activity relationship (QSAR) analysis uses structural, quantum chemical, and physicochemical features calculated from molecular geometry as explanatory variables predicting physiological activity. Recently, deep learning based ...

Automated retinopathy of prematurity screening using deep neural networks.

EBioMedicine
BACKGROUND: Retinopathy of prematurity (ROP) is the leading cause of childhood blindness worldwide. Automated ROP detection system is urgent and it appears to be a safe, reliable, and cost-effective complement to human experts.

Application of machine-learning to predict early spontaneous preterm birth among nulliparous non-Hispanic black and white women.

Annals of epidemiology
PURPOSE: Spontaneous preterm birth is a leading cause of perinatal mortality in the United States, occurring disproportionately among non-Hispanic black women compared to other race-ethnicities. Clinicians lack tools to identify first-time mothers at...

Multimodal Assessment of Parkinson's Disease: A Deep Learning Approach.

IEEE journal of biomedical and health informatics
Parkinson's disease is a neurodegenerative disorder characterized by a variety of motor symptoms. Particularly, difficulties to start/stop movements have been observed in patients. From a technical/diagnostic point of view, these movement changes can...

Convolutional Neural Network Using a Breast MRI Tumor Dataset Can Predict Oncotype Dx Recurrence Score.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: Oncotype Dx is a validated genetic analysis that provides a recurrence score (RS) to quantitatively predict outcomes in patients who meet the criteria of estrogen receptor positive / human epidermal growth factor receptor-2 negative (ER+/...

Automated deep-neural-network surveillance of cranial images for acute neurologic events.

Nature medicine
Rapid diagnosis and treatment of acute neurological illnesses such as stroke, hemorrhage, and hydrocephalus are critical to achieving positive outcomes and preserving neurologic function-'time is brain'. Although these disorders are often recognizabl...

Predicting diabetic retinopathy and identifying interpretable biomedical features using machine learning algorithms.

BMC bioinformatics
BACKGROUND: The risk factors of diabetic retinopathy (DR) were investigated extensively in the past studies, but it remains unknown which risk factors were more associated with the DR than others. If we can detect the DR related risk factors more acc...