AIMC Topic: Sarcopenia

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Prognostic networks for unraveling the biological mechanisms of Sarcopenia.

Mechanisms of ageing and development
Sarcopenia is an age-related multifactorial process that involved several biological mechanisms, whose specific contribution and interplay is still unknown. The present study proposes prognostic networks based on machine learning approaches to unrave...

Machine Learning for Automatic Paraspinous Muscle Area and Attenuation Measures on Low-Dose Chest CT Scans.

Academic radiology
RATIONALE AND OBJECTIVES: To develop and evaluate an automated machine learning (ML) algorithm for segmenting the paraspinous muscles on chest computed tomography (CT) scans to evaluate for presence of sarcopenia.

Sarcopenia: Beyond Muscle Atrophy and into the New Frontiers of Opportunistic Imaging, Precision Medicine, and Machine Learning.

Seminars in musculoskeletal radiology
As populations continue to age worldwide, the impact of sarcopenia on public health will continue to grow. The clinically relevant and increasingly common diagnosis of sarcopenia is at the confluence of three tectonic shifts in medicine: opportunisti...

Exploring the link between the ZJU index and sarcopenia in adults aged 20-59 using NHANES and machine learning.

Scientific reports
Sarcopenia, characterized by progressive loss of muscle mass and function, is a growing public health concern. The ZJU index, a novel metabolic marker, integrates lipid metabolism and glucose regulation parameters. While its association with metaboli...

Development and Validation of Quantile Regression Forests for Prediction of Reference Quantiles in Handgrip and Chair-Stand Test.

Journal of cachexia, sarcopenia and muscle
BACKGROUND: Muscle strength is one of the key components in the diagnosis of sarcopenia. The aim of this study was to train a machine learning model to predict reference values and percentiles for handgrip strength and chair-stand test (CST), in a la...

Comparison of Sarcopenia Assessment in Liver Transplant Recipients by Computed Tomography Freehand Region-of-Interest versus an Automated Deep Learning System.

Clinical transplantation
INTRODUCTION: Sarcopenia, or the loss of muscle quality and quantity, has been associated with poor clinical outcomes in liver transplantation such as infection, increased length of stay, and increased patient mortality. Abdominal computed tomography...

Update on the detection of frailty in older adults: a multicenter cohort machine learning-based study protocol.

Aging
BACKGROUND: This study aims to investigate the relationship between muscle activation variables assessed via ultrasound and the comprehensive assessment of geriatric patients, as well as to analyze ultrasound images to determine their correlation wit...

Towards Precision in Sarcopenia Assessment: The Challenges of Multimodal Data Analysis in the Era of AI.

International journal of molecular sciences
Sarcopenia, a condition characterised by the progressive decline in skeletal muscle mass and function, presents significant challenges in geriatric healthcare. Despite advances in its management, complex etiopathogenesis and the heterogeneity of diag...

Diagnosis of Sarcopenia Using Convolutional Neural Network Models Based on Muscle Ultrasound Images: Prospective Multicenter Study.

Journal of medical Internet research
BACKGROUND: Early detection is clinically crucial for the strategic handling of sarcopenia, yet the screening process, which includes assessments of muscle mass, strength, and function, remains complex and difficult to access.