AIMC Topic: Schizophrenia

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Detecting Abnormal Brain Regions in Schizophrenia Using Structural MRI via Machine Learning.

Computational intelligence and neuroscience Apr 5, 2020
Utilizing neuroimaging and machine learning (ML) to differentiate schizophrenia (SZ) patients from normal controls (NCs) and for detecting abnormal brain regions in schizophrenia has several benefits and can provide a reference for the clinical diagn...
Image Interpretation, Computer-Assisted Humans Male Neuroimaging Machine Learning Middle Aged Brain Magnetic Resonance Imaging Female Schizophrenia Adult
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Dynamic ElecTronic hEalth reCord deTection (DETECT) of individuals at risk of a first episode of psychosis: a case-control development and validation study.

The Lancet. Digital health Mar 26, 2020
BACKGROUND: Many individuals who will experience a first episode of psychosis (FEP) are not detected before occurrence, limiting the effect of preventive interventions. The combination of machine-learning methods and electronic health records (EHRs) ...
Cohort Studies Machine Learning Humans Male Data Analysis Schizophrenia ROC Curve Prognosis Middle Aged Neural Networks, Computer Risk Assessment Psychotic Disorders Data Management Delivery of Health Care Retrospective Studies Case-Control Studies Datasets as Topic Databases, Factual Area Under Curve Electronic Health Records Models, Biological Female Adult
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Will machine learning applied to neuroimaging in bipolar disorder help the clinician? A critical review and methodological suggestions.

Bipolar disorders Mar 20, 2020
OBJECTIVES: The existence of anatomofunctional brain abnormalities in bipolar disorder (BD) is now well established by magnetic resonance imaging (MRI) studies. To create diagnostic and prognostic tools, as well as identifying biologically valid subt...
Brain Female Reproducibility of Results Adult Male Humans Machine Learning Algorithms Schizophrenia Neuroimaging Middle Aged Depressive Disorder, Major Bipolar Disorder Magnetic Resonance Imaging
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Feature optimization method for machine learning-based diagnosis of schizophrenia using magnetoencephalography.

Journal of neuroscience methods Mar 19, 2020
BACKGROUND: When many features and a small number of clinical data exist, previous studies have used a few top-ranked features from the Fisher's discriminant ratio (FDR) for feature selection. However, there are many similarities between selected fea...
Machine Learning Brain Brain Mapping Schizophrenia Magnetoencephalography Humans
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Pragmatics, Theory of Mind and executive functions in schizophrenia: Disentangling the puzzle using machine learning.

PloS one Mar 3, 2020
OBJECTIVE: Schizophrenia is associated with a severe impairment in the communicative-pragmatic domain. Recent research has tried to disentangle the relationship between communicative impairment and other domains usually impaired in schizophrenia, i.e...
Female Young Adult Adult Communication Male Middle Aged Case-Control Studies Linguistics Memory, Short-Term Cognition Schizophrenic Psychology Bayes Theorem Schizophrenia Theory of Mind Neuropsychological Tests Executive Function Models, Psychological Social Communication Disorder Humans Machine Learning
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Diagnosing schizophrenia with network analysis and a machine learning method.

International journal of methods in psychiatric research Feb 5, 2020
OBJECTIVE: Schizophrenia is a chronic and debilitating neuropsychiatric disorder. It has been suggested that impaired brain connectivity underlies the pathophysiology of schizophrenia. Network analysis has thus recently emerged in the field of schizo...
Humans Machine Learning Brain Models, Statistical Female Schizophrenia Adult Diffusion Tensor Imaging Male Support Vector Machine
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Development and Validation of a Machine Learning Individualized Treatment Rule in First-Episode Schizophrenia.

JAMA network open Feb 5, 2020
IMPORTANCE: Little guidance exists to date on how to select antipsychotic medications for patients with first-episode schizophrenia.
Clinical Decision Rules Female Young Adult Adult Male Middle Aged Treatment Outcome Models, Statistical Schizophrenia Antipsychotic Agents Machine Learning Precision Medicine Prognosis Humans Retrospective Studies
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A Multidimensional Neural Maturation Index Reveals Reproducible Developmental Patterns in Children and Adolescents.

The Journal of neuroscience : the official journal of the Society for Neuroscience Jan 2, 2020
Adolescence is a time of extensive neural restructuring, leaving one susceptible to atypical development. Although neural maturation in humans can be measured using functional and structural MRI, the subtle patterns associated with the initial stages...
Magnetic Resonance Imaging Schizophrenia Neuroimaging Humans Male Brain Adolescent Female Child Young Adult Image Processing, Computer-Assisted Support Vector Machine
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DeepMiR2GO: Inferring Functions of Human MicroRNAs Using a Deep Multi-Label Classification Model.

International journal of molecular sciences Nov 30, 2019
MicroRNAs (miRNAs) are a highly abundant collection of functional non-coding RNAs involved in cellular regulation and various complex human diseases. Although a large number of miRNAs have been identified, most of their physiological functions remain...
Gene Expression Regulation Gene Regulatory Networks Humans MicroRNAs Neural Networks, Computer Gene Ontology Schizophrenia Cardiovascular Diseases Datasets as Topic Neoplasms
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Integrating machining learning and multimodal neuroimaging to detect schizophrenia at the level of the individual.

Human brain mapping Nov 18, 2019
Schizophrenia is a severe psychiatric disorder associated with both structural and functional brain abnormalities. In the past few years, there has been growing interest in the application of machine learning techniques to neuroimaging data for the d...
Multimodal Imaging Schizophrenia Rest Neuroimaging Gray Matter Middle Aged Image Processing, Computer-Assisted Support Vector Machine Magnetic Resonance Imaging Humans Machine Learning White Matter Female Connectome Reproducibility of Results Neural Pathways Young Adult Diffusion Tensor Imaging Adult Male
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