BACKGROUND: Early identification of Schizophrenia Spectrum Disorder (SSD) is crucial for effective intervention and prognosis improvement. Previous neuroimaging-based classifications have primarily focused on chronic, medicated SSD cohorts. However, ...
Schizophrenia (SZ) and bipolar disorder (BD) pose diagnostic challenges due to overlapping clinical symptoms and genetic factors, often resulting in misdiagnosis and suboptimal treatment outcomes. This study aimed to identify EEG-based biomarkers tha...
There is a notable need of quantifiable and objective methods for the classification of schizophrenia. Patients with schizophrenia exhibit atypical eye movements compared with healthy individuals. To address this need, we have developed a classificat...
BACKGROUND: Schizophrenia (SCH) is a complex neurodevelopmental disorder, whose pathogenesis is not fully elucidated. This article aims to reveal disease-specific brain structural and functional changes and their potential genetic basis by analyzing ...
Schizophrenia is a complicated mental condition marked by disruptions in thought processes, perceptions, and emotional responses, which can cause severe impairment in everyday functioning. sMRI is a non-invasive neuroimaging technology that visualize...
Clozapine is widely regarded as one of the most effective therapeutics for treatment-resistant schizophrenia. Despite its proven efficacy, the therapeutic use of clozapine is complicated by its narrow therapeutic index, which necessitates rapid and p...
Schizophrenia (SZ) is a complex mental disorder characterized by a profound disruption in cognition and emotion, often resulting in a distorted perception of reality. Magnetic resonance imaging (MRI) is an essential tool for diagnosing SZ which helps...
International journal of molecular sciences
Mar 4, 2025
Diagnostic practices for schizophrenia are unreliable due to the lack of a stable biomarker. However, machine learning holds promise in aiding in the diagnosis of schizophrenia and other neurological disorders. Dysregulated miRNAs were extracted from...
Within precision psychiatry, there is a growing interest in normative models given their ability to parse heterogeneity. While they are intuitive and informative, the technical expertise and resources required to develop normative models may not be a...
Progress in neuro-psychopharmacology & biological psychiatry
Feb 25, 2025
Schizophrenia is a complex mental disorder. Accurate diagnosis and classification of schizophrenia has always been a major challenge in clinic due to the lack of biomarkers. Therefore, identifying molecular biomarkers, particularly in the peripheral ...
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