AIMC Topic: Schizophrenia

Clear Filters Showing 261 to 270 of 327 articles

The Retinal Age Gap as a Marker of Accelerated Aging in the Early Course of Schizophrenia.

Schizophrenia bulletin
BACKGROUND AND HYPOTHESIS: Given the available findings confirming accelerated brain aging in schizophrenia (SZ), we conducted a study aimed at verifying whether quantitative retinal morphological data enable age prediction and whether schizophrenia ...

Exploring Primary and Interaction Effects of Minor Physical Anomalies: Development and Validation of Prediction Models Using Explainable Machine Learning Algorithms for Early-Onset Schizophrenia.

Schizophrenia bulletin
BACKGROUND AND HYPOTHESIS: Minor physical abnormalities (MPAs) are neurodevelopmental markers that can be traced to prenatal events and may be significant features of early-onset schizophrenia (EOS). Therefore, our study aimed to (1) find the primary...

Comparative cytokine signatures and cognitive deficits in early-onset schizophrenia and adolescent major depression: Toward refined diagnostic classification frameworks.

Journal of affective disorders
BACKGROUND: This study analyzed plasma cytokine patterns in individuals with schizophrenia (SCZ), major depressive disorder (MDD), and healthy controls, explored the link between cytokine levels and cognitive function, and created machine learning mo...

A scientometric analysis of machine learning in schizophrenia neuroimaging: Trends and insights (2012-2024).

Journal of affective disorders
Machine learning applications in schizophrenia neuroimaging research have undergone significant evolution since 2012. However, a comprehensive scientometric analysis of this field has not yet been conducted. This study analyzed 315 original research ...

Towards an Integrative Account of Potential Mechanisms Mediating the Path From Sleep Dysfunction to Hallucinations.

Schizophrenia bulletin
BACKGROUND: Sleep dysfunction shares a bidirectional relationship with hallucinatory experiences, with the strongest path from sleep dysfunction to the occurrence of hallucinatory experiences. This review aimed to identify potential mechanisms throug...

Efficacy of User Self-Led and Human-Supported Digital Health Interventions for People With Schizophrenia: A Systematic Review and Meta-Analysis.

Schizophrenia bulletin
BACKGROUND: Digital health interventions (DHIs) may enable low cost, scalable improvements in the quality of care for adults with schizophrenia. Given the fast-growing number of studies using these tools, this review aimed to assess the efficacy and ...

Efficacy of rTMS on SCZ symptoms: Insights from connectome mapping.

Psychiatry research
Repetitive transcranial magnetic stimulation (rTMS) is a potential treatment for schizophrenia (SCZ), yet its efficacy and underlying mechanisms remain uncertain. This study evaluates the impact of rTMS targeting the right orbitofrontal cortex (OFC) ...

RIPTOSO: The development of a screening tool for adverse events during forensic-psychiatric inpatient treatments of offenders with schizophrenia spectrum disorders.

Psychiatry research
Adverse events such as compulsory measures, absconding, illicit substance use, self-harm, aggressive behavior, and prolonged hospitalization pose significant challenges in forensic psychiatric inpatient care. This study introduces a machine learning-...

Modeling the Determinants of Subjective Well-Being in Schizophrenia.

Schizophrenia bulletin
BACKGROUND: The ultimate goal of successful schizophrenia treatment is not just to alleviate psychotic symptoms, but also to reduce distress and achieve subjective well-being (SWB). We aimed to identify the determinants of SWB and their interrelation...

Distinct processing stages of cross-modal conflict in schizophrenia: The role of auditory cortex underactivation.

Schizophrenia research
BACKGROUND: The cross-modal conflict deficit is a key feature of schizophrenia. However, it remains largely unknown whether cross-modal conflict in schizophrenia diverges at distinct processing stages and its potential association with the auditory c...