AIMC Topic: Sensitivity and Specificity

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Automatic classification of apnea/hypopnea events through sleep/wake states and severity of SDB from a pulse oximeter.

Physiological measurement
This study proposes a method of automatically classifying sleep apnea/hypopnea events based on sleep states and the severity of sleep-disordered breathing (SDB) using photoplethysmogram (PPG) and oxygen saturation (SpO2) signals acquired from a pulse...

A systematic comparison of feature space effects on disease classifier performance for phenotype identification of five diseases.

Journal of biomedical informatics
Automated phenotype identification plays a critical role in cohort selection and bioinformatics data mining. Natural Language Processing (NLP)-informed classification techniques can robustly identify phenotypes in unstructured medical notes. In this ...

Multi-scale deep networks and regression forests for direct bi-ventricular volume estimation.

Medical image analysis
Direct estimation of cardiac ventricular volumes has become increasingly popular and important in cardiac function analysis due to its effectiveness and efficiency by avoiding an intermediate segmentation step. However, existing methods rely on eithe...

Identification of Heat Shock Protein families and J-protein types by incorporating Dipeptide Composition into Chou's general PseAAC.

Computer methods and programs in biomedicine
Heat Shock Proteins (HSPs) are the substantial ingredients for cell growth and viability, which are found in all living organisms. HSPs manage the process of folding and unfolding of proteins, the quality of newly synthesized proteins and protecting ...

Retinal vessel segmentation using multi-scale textons derived from keypoints.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
This paper presents a retinal vessel segmentation algorithm which uses a texton dictionary to classify vessel/non-vessel pixels. However, in contrast to previous work where filter parameters are learnt from manually labelled image pixels our filter p...

A Bayesian approach to distinguishing interdigitated tongue muscles from limited diffusion magnetic resonance imaging.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
The tongue is a critical organ for a variety of functions, including swallowing, respiration, and speech. It contains intrinsic and extrinsic muscles that play an important role in changing its shape and position. Diffusion tensor imaging (DTI) has b...

Exploring multifractal-based features for mild Alzheimer's disease classification.

Magnetic resonance in medicine
PURPOSE: Multifractal applications to resting state functional MRI (rs-fMRI) time series for diagnosing Alzheimer's disease (AD) are still limited. We aim to address two issues: (I) if and what multifractal features are sufficiently discriminative to...

Automated, high-throughput serum glycoprofiling platform.

Integrative biology : quantitative biosciences from nano to macro
Complex carbohydrates are rapidly becoming excellent biomarker candidates because of their high sensitivity to pathological changes. However, the discovery of clinical glycobiomarkers has been slow, due to the scarcity of high-throughput glycoanalyti...