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Severity of Illness Index

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Development and Validation of a Prediction Model for Co-Occurring Moderate-to-Severe Anxiety Symptoms in First-Episode and Drug Naïve Patients With Major Depressive Disorder.

Depression and anxiety
Moderate-to-severe anxiety symptoms are severe and common in patients with major depressive disorder (MDD) and have a significant impact on MDD patients and their families. The main objective of this study was to develop a risk prediction model for ...

Machine Learning Identifies Clinically Distinct Phenotypes in Patients With Aortic Regurgitation.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
BACKGROUND: Aortic regurgitation (AR) is a prevalent valve disease with a long latent period before symptoms appear. Recent data has suggested the role of novel markers of myocardial overload in assessing onset of decompensation.

Predicting stroke severity of patients using interpretable machine learning algorithms.

European journal of medical research
BACKGROUND: Stroke is a significant global health concern, ranking as the second leading cause of death and placing a substantial financial burden on healthcare systems, particularly in low- and middle-income countries. Timely evaluation of stroke se...

Advantages of Metabolomics-Based Multivariate Machine Learning to Predict Disease Severity: Example of COVID.

International journal of molecular sciences
The COVID-19 outbreak caused saturations of hospitals, highlighting the importance of early patient triage to optimize resource prioritization. Herein, our objective was to test if high definition metabolomics, combined with ML, can improve prognosti...

Identification of TXN and F5 as novel diagnostic gene biomarkers of the severe asthma based on bioinformatics and machine learning analysis.

Autoimmunity
Asthma poses a major threat to human health. The aim of this study was to identify genetic markers of severe asthma and analyze the relationship between key genes and immune infiltration. Differentially expressed genes (DEGs) were first screened by d...

Exploring the potential of large language models in identifying metabolic dysfunction-associated steatotic liver disease: A comparative study of non-invasive tests and artificial intelligence-generated responses.

Liver international : official journal of the International Association for the Study of the Liver
BACKGROUND AND AIMS: This study sought to assess the capabilities of large language models (LLMs) in identifying clinically significant metabolic dysfunction-associated steatotic liver disease (MASLD).

A deep learning-based method for assessing tricuspid regurgitation using continuous wave Doppler spectra.

Scientific reports
Transthoracic echocardiography (TTE) is widely recognized as one of the principal modalities for diagnosing tricuspid regurgitation (TR). The diagnostic procedures associated with conventional methods are intricate and labor-intensive, with human err...

Machine learning adjusted sequential CUSUM-analyses are superior to cross-sectional analysis of excess mortality after surgery.

International journal of medical informatics
BACKGROUND: The assessment of clinical outcome quality, particularly in surgery, is crucial for healthcare improvement. Traditional cross-sectional analyses often fall short in timely and systematic identification of clinical quality issues. This stu...

Reliable and easy-to-use calculating tool for the Nail Psoriasis Severity Index using deep learning.

NPJ systems biology and applications
Since nail psoriasis restricts the patient's daily activities, therapeutic intervention based on reliable and reproducible evaluation is critical. The Nail Psoriasis Severity Index (NAPSI) is a validated scoring tool, but its usefulness is limited by...

Improved patient identification by incorporating symptom severity in deep learning using neuroanatomic images in first episode schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Brain alterations associated with illness severity in schizophrenia remain poorly understood. Establishing linkages between imaging biomarkers and symptom expression may enhance mechanistic understanding of acute psychotic illness. Constructing model...