AIMC Topic: Sex Characteristics

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Common and unique brain aging patterns between females and males quantified by large-scale deep learning.

Human brain mapping
There has been extensive evidence that aging affects human brain function. However, there is no complete picture of what brain functional changes are mostly related to normal aging and how aging affects brain function similarly and differently betwee...

Machine learning trial to detect sex differences in simple sticker arts of 1606 preschool children.

Minerva pediatrics
BACKGROUND: Previous studies suggested that drawings made by preschool boys and girls show distinguishable differences. However, children's drawings on their own are too complexly determined and inherently ambiguous to be a reliable indicator. In the...

SPIN: sex-specific and pathway-based interpretable neural network for sexual dimorphism analysis.

Briefings in bioinformatics
Sexual dimorphism in prevalence, severity and genetic susceptibility exists for most common diseases. However, most genetic and clinical outcome studies are designed in sex-combined framework considering sex as a covariate. Few sex-specific studies h...

Sex classification from functional brain connectivity: Generalization to multiple datasets.

Human brain mapping
Machine learning (ML) approaches are increasingly being applied to neuroimaging data. Studies in neuroscience typically have to rely on a limited set of training data which may impair the generalizability of ML models. However, it is still unclear wh...

Sex Differences of Brain Functional Topography Revealed in Normal Aging and Alzheimer's Disease Cohort.

Journal of Alzheimer's disease : JAD
We applied graph theory analysis on resting-state functional magnetic resonance imaging data to evaluate sex differences of brain functional topography in normal controls (NCs), early mild cognitive impairment (eMCI), and AD patients. These metrics w...

Facial Recognition Neural Networks Confirm Success of Facial Feminization Surgery.

Plastic and reconstructive surgery
BACKGROUND: Male-to-female transgender patients desire to be identified, and treated, as female, in public and social settings. Facial feminization surgery entails a combination of highly visible changes in facial features. To study the effectiveness...

Beyond Human Perception: Sexual Dimorphism in Hand and Wrist Radiographs Is Discernible by a Deep Learning Model.

Journal of digital imaging
Despite the well-established impact of sex and sex hormones on bone structure and density, there has been limited description of sexual dimorphism in the hand and wrist in the literature. We developed a deep convolutional neural network (CNN) model t...

Utility of the morphometry of the maxillary sinuses for gender determination by using computed tomography.

Dental and medical problems
BACKGROUND: It is impossible to use the routine skeletal parts for gender identification if the skeleton of unknown human remains is obtained in a fragmented and incomplete state. The alternative is to use other parts of the skeleton for gender ident...

Relation of Age, Sex and Bone Mineral Density to Serum 25-Hydroxyvitamin D Levels in Chinese Women and Men.

Orthopaedic surgery
OBJECTIVE: To investigate the relation of circulating 25-hydroxyvitamin D (25[OH]D) levels to age, sex, and bone mineral density (BMD) in adults living in Guangzhou Province.