AIMC Topic: Software

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Automated deep learning segmentation of neuritic plaques and neurofibrillary tangles in Alzheimer disease brain sections using a proprietary software.

Journal of neuropathology and experimental neurology
Neuropathological diagnosis of Alzheimer disease (AD) relies on semiquantitative analysis of phosphorylated tau-positive neurofibrillary tangles (NFTs) and neuritic plaques (NPs), without consideration of lesion heterogeneity in individual cases. We ...

Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps.

JAMA
IMPORTANCE: Accurate assessment of gestational age (GA) is essential to good pregnancy care but often requires ultrasonography, which may not be available in low-resource settings. This study developed a deep learning artificial intelligence (AI) mod...

Semantic Mapping of Named-Entities in openEHR Templates and Ad-hoc Generation of Compositions.

Studies in health technology and informatics
Integration of free texts from reports written by physicians to an interoperable standard is important for improving patient-centric care and research in the medical domain. In the context of unstructured clinical data, NLP Information Extraction ser...

OntoBridge Versus Traditional ETL: Enhancing Data Standardization into CDM Formats Using Ontologies Within the DATOS-CAT Project.

Studies in health technology and informatics
Common Data Models (CDMs) enhance data exchange and integration across diverse sources, preserving semantics and context. Transforming local data into CDMs is typically cumbersome and resource-intensive, with limited reusability. This article compare...

AI in microbiome research: Where have we been, where are we going?

Cell host & microbe
Artificial intelligence (AI), a subdiscipline of computer science that develops machines or software that mimic characteristically human cognitive functions, is currently undergoing a revolution. In this commentary article, I will give my perspective...

Advancing mRNA subcellular localization prediction with graph neural network and RNA structure.

Bioinformatics (Oxford, England)
MOTIVATION: The asymmetrical distribution of expressed mRNAs tightly controls the precise synthesis of proteins within human cells. This non-uniform distribution, a cornerstone of developmental biology, plays a pivotal role in numerous cellular proce...

BertSNR: an interpretable deep learning framework for single-nucleotide resolution identification of transcription factor binding sites based on DNA language model.

Bioinformatics (Oxford, England)
MOTIVATION: Transcription factors are pivotal in the regulation of gene expression, and accurate identification of transcription factor binding sites (TFBSs) at high resolution is crucial for understanding the mechanisms underlying gene regulation. T...

New GO-based measures in multiple network alignment.

Bioinformatics (Oxford, England)
MOTIVATION: Protein-protein interaction (PPI) networks provide valuable insights into the function of biological systems. Aligning multiple PPI networks may expose relationships beyond those observable by pairwise comparisons. However, assessing the ...

Artificial intelligence software for analysing chest X-ray images to identify suspected lung cancer: an evidence synthesis early value assessment.

Health technology assessment (Winchester, England)
BACKGROUND: Lung cancer is one of the most common types of cancer in the United Kingdom. It is often diagnosed late. The 5-year survival rate for lung cancer is below 10%. Early diagnosis may improve survival. Software that has an artificial intellig...