AIMC Topic: Spectrometry, Fluorescence
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Design of a calix[4]arene-functionalized metal-organic framework probe for highly sensitive and selective monitor of hippuric acid for indexing toluene exposure.
Analytica chimica acta
Nov 23, 2017
In the present work, a novel metal-organic framework (MOF) fluorescent probe was prepared by post-synthetic modification of MIL-53-NH(Al) with carboxylatocalix[4]arene (CC[4]A). The introduced CC[4]A could not only enhance the fluorescence performanc...
Integrating DNA structure switch with branched hairpins for the detection of uracil-DNA glycosylase activity and inhibitor screening.
Talanta
Nov 22, 2017
The detection of uracil-DNA glycosylase (UDG) activity is pivotal for its biochemical studies and the development of drugs for UDG-related diseases. Here, we explored an integrated DNA structure switch for high sensitive detection of UDG activity. Th...
Modification-free carbon dots as turn-on fluorescence probe for detection of organophosphorus pesticides.
Food chemistry
Nov 11, 2017
It is important to detect pesticides residues due to the concern over food safety. In this work, the burning ash of waste paper was used as carbon source to synthesize carbon dots (C-dots). The fluorescence of obtained C-dots could been turn off by F...
A hierarchical classifier based on human blood plasma fluorescence for non-invasive colorectal cancer screening.
Artificial intelligence in medicine
Sep 20, 2017
Colorectal cancer (CRC) a leading cause of death by cancer, and screening programs for its early identification are at the heart of the increasing survival rates. To motivate population participation, non-invasive, accurate, scalable and cost-effecti...
Stability-indicating spectrofluorimetric method with enhanced sensitivity for determination of vancomycin hydrochloride in pharmaceuticals and spiked human plasma: Application to degradation kinetics.
Journal of food and drug analysis
Jul 8, 2017
Based on investigating the relative fluorescence intensity of vancomycin hydrochloride (VCM) in methanol, a simple, highly sensitive, time-saving and specific spectrofluorimetric method was developed and validated. VCM fluorescence was measured at 33...
Sensitive fluorescent detection of DNA methyltransferase using nicking endonuclease-mediated multiple primers-like rolling circle amplification.
Biosensors & bioelectronics
Dec 30, 2016
Sensitive and reliable detection of DNA methyltransferase (MTase) is of great significance for both early tumor diagnosis and therapy. In this study, a simple, label-free and sensitive DNA MTase-sensing method was developed on the basis of a nicking ...
Oil species identification technique developed by Gabor wavelet analysis and support vector machine based on concentration-synchronous-matrix-fluorescence spectroscopy.
Marine pollution bulletin
Jan 13, 2016
Concentration-synchronous-matrix-fluorescence (CSMF) spectroscopy was applied to discriminate the oil species by characterizing the concentration dependent fluorescence properties of petroleum related samples. Seven days weathering experiment of 3 cr...
Application of unfolded principal component analysis-radial basis function neural network for determination of celecoxib in human serum by three-dimensional excitation-emission matrix fluorescence spectroscopy.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Dec 8, 2014
This study describes a simple and rapid approach of monitoring celecoxib (CLX). Unfolded principal component analysis-radial basis function neural network (UPCA-RBFNN) and excitation-emission spectra were combined to develop new model in the determin...
One-pot synthesized multifunctional Zn-MOF/HOF heterostructure sensor array assisted by machine learning for efficient capture, target discrimination and optosmart sensing of doxycycline analogs.
Journal of hazardous materials
Aug 15, 2025
The ideal multifunctional platform that combines the capabilities of effective capture, sensitive detection, and accurate identification of doxycycline analogs (DCs) remains a serious challenge for ensuring the environment and food security. This wor...
Dual-mode nanosensor for sensitive detection of methotrexate based on fluorescence technology and deep learning algorithms.
Analytica chimica acta
Aug 8, 2025
BACKGROUND: Methotrexate (MTX) in the body can result in severe, potentially life-threatening side effects. As a result, it is imperative to establish a dependable, precise, and specific method for detecting MTX. However, conventional sensors often s...
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