AIMC Topic: Spectroscopy, Fourier Transform Infrared

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Advancing frontline early pancreatic cancer detection using within-class feature extraction in FTIR spectroscopy.

Scientific reports
This study introduces a novel approach for the early detection of pancreatic cancer through biofluid spectroscopy, leveraging a unique machine learning pipeline comprising class-specific principal component analysis (PCA), linear discriminant analysi...

Urine Analysed by FTIR, Chemometrics and Machine Learning Methods in Determination Spectroscopy Marker of Prostate Cancer in Urine.

Journal of biophotonics
Prostate-specific antigen (PSA) is the most commonly used marker of prostate cancer. However, nearly 25% of men with elevated PSA levels do not have cancer and nearly 20% of patients with prostate cancer have normal serum PSA levels. Therefore, in th...

Enhancing the accuracy of blood-glucose tests by upgrading FTIR with multiple-reflections, quantum cascade laser, two-dimensional correlation spectroscopy and machine learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The accuracy of screening diabetes from non-diabetes is drastically enhanced by strategically upgrading the bench-marking infrared spectroscopy technique for non-invasive tests of blood-glucose, both with state-of-the-art instrumentation-retrofits an...

Innovative label-free lymphoma diagnosis using infrared spectroscopy and machine learning on tissue sections.

Communications biology
The diagnosis of lymphomas is challenging due to their diverse histological presentations and clinical manifestations. There is a need for inexpensive tools that require minimal expertise and are accessible for routine laboratories. Contrastingly, cu...

A new approach to assess post-mortem interval: A machine learning-assisted label-free ATR-FTIR analysis of human vitreous humor.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
A crucial issue in forensics is determining the post-mortem interval (PMI), the time between death and the finding of a body. Despite various methods already employed for its estimation, only approximate values are currently achievable. Vitreous humo...

Chemical composition alterations in rat brain hypothalamus induced by irisin administration using spectroscopic and machine learning techniques.

Analytical biochemistry
This study employed Fourier transform infrared (FTIR) spectroscopy to determine the chemical composition of brain tissues and the changes induced by irisin at doses of 50 mg and 100 mg. Brain tissues were collected from control rats and those adminis...

Machine learning assisted rapid approach for quantitative prediction of biochemical parameters of blood serum with FTIR spectroscopy.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study develops regression models for predicting blood biochemical data using Fourier-transform infrared spectroscopy (FTIR) analysis. Absorption at specific wavelengths of blood serum is revealed to have strong correlations with biochemical para...

A novel approach to the cause of death identification-multi-strategy integration of multi-organ FTIR spectroscopy information using machine learning.

Talanta
Identifying the cause of death has always been a major focus and challenge in forensic practice and research. Traditional techniques for determining the causes of death are time-consuming, labor-intensive, have high professional barriers, and are vul...

Molecular profiling of blood plasma-derived extracellular vesicles derived from Duchenne muscular dystrophy patients through integration of FTIR spectroscopy and machine learning reveals disease signatures.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
PURPOSE: To identify and monitor the FTIR spectral signatures of plasma extracellular vesicles (EVs) from Duchenne Muscular Dystrophy (DMD) patients at different stages with Healthy controls using machine learning models.

Machine learning prediction of stalk lignin content using Fourier transform infrared spectroscopy in large scale maize germplasm.

International journal of biological macromolecules
Lignin has been recognized as a major factor contributing to lignocellulosic recalcitrance in biofuel production and attracted attentions as a high-value product in the biorefinery field. As the traditional wet chemical methods for detecting lignin c...