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Stress, Mechanical

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A novel machine learning based computational framework for homogenization of heterogeneous soft materials: application to liver tissue.

Biomechanics and modeling in mechanobiology
Real-time simulation of organs increases comfort and safety for patients during the surgery. Proper generalized decomposition (PGD) is an efficient numerical method with coordinate errors below 1 mm and response time below 0.1 s that can be used for ...

Machine learning-based design strategy for 3D printable bioink: elastic modulus and yield stress determine printability.

Biofabrication
Although three-dimensional (3D) bioprinting technology is rapidly developing, the design strategies for biocompatible 3D-printable bioinks remain a challenge. In this study, we developed a machine learning-based method to design 3D-printable bioink u...

Quantification of Mechanical Forces and Physiological Processes Involved in Pollen Tube Growth Using Microfluidics and Microrobotics.

Methods in molecular biology (Clifton, N.J.)
Pollen tubes face many obstacles on their way to the ovule. They have to decide whether to navigate around cells or penetrate the cell wall and grow through it or even within it. Besides chemical sensing, which directs the pollen tubes on their path ...

Human-mimetic soft robot joint for shock absorption through joint dislocation.

Bioinspiration & biomimetics
This paper presents a human-mimetic manipulator capable of shock absorption by using dislocation at the soft joint. A one degree-of-freedom (DOF) soft robot joint was developed based on the human elbow-joint structure, especially mimicking the humero...

An earthworm-inspired soft robot with perceptive artificial skin.

Bioinspiration & biomimetics
The bodies of earthworms are composed of repeating deformable structural units, called metameres, that generate the peristaltic body motions required for limbless underground burrowing and above-ground crawling. Metameres are actuated by circular and...

Elasticity Versus Hyperelasticity Considerations in Quasistatic Modeling of a Soft Finger-Like Robotic Appendage for Real-Time Position and Force Estimation.

Soft robotics
Various methods based on hyperelastic assumptions have been developed to address the mathematical complexities of modeling motion and deformation of continuum manipulators. In this study, we propose a quasistatic approach for 3D modeling and real-tim...

On the use of machine learning techniques for the mechanical characterization of soft biological tissues.

International journal for numerical methods in biomedical engineering
Motivated by the search for new strategies for fitting a material model, a new approach is explored in the present work. The use of numerical and complex algorithms based on machine learning techniques such as support vector machines for regression, ...

Machine learning-aided exploration of relationship between strength and elastic properties in ascending thoracic aneurysm.

International journal for numerical methods in biomedical engineering
Machine learning was applied to classify tension-strain curves harvested from inflation tests on ascending thoracic aneurysm samples. The curves were classified into rupture and nonrupture groups using prerupture response features. Two groups of feat...

Performance metrics for guidance active constraints in surgical robotics.

The international journal of medical robotics + computer assisted surgery : MRCAS
Active constraint (AC)/virtual fixture (VF) is among the most popular approaches towards the shared execution of subtasks by the surgeon and robotic systems. As more possibilities appear for the implementation of ACs in surgical scenarios, the need t...

Biomechanics of the Healthy and Keratoconic Corneas: A Combination of the Clinical Data, Finite Element Analysis, and Artificial Neural Network.

Current pharmaceutical design
BACKGROUND: Keratoconus is recognized by asymmetrical thinning and bulging of the cornea, resulting in distortion in the surface of the cornea. Keratoconus also alters the biomechanical properties of the cornea, which can be an indicator of the healt...