BACKGROUND: Electroencephalography (EEG) is a noninvasive, cost-effective, and robust tool, which directly measures in vivo neuronal mass activity with high temporal resolution. Combined with state-of-the-art machine learning (ML) techniques, EEG rec...
Journal of the American Medical Informatics Association : JAMIA
May 1, 2025
OBJECTIVE: This study aimed to develop a novel multi-stage self-supervised learning model tailored for the accurate classification of optical coherence tomography (OCT) images in ophthalmology reducing reliance on costly labeled datasets while mainta...
White matter hyperintensities (WMH) are neuroimaging markers linked to an elevated risk of cognitive decline. WMH severity is typically assessed via visual rating scales and through volumetric segmentation. While visual rating scales are commonly use...
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2025
BACKGROUND: With the global population aging and advancements in the medical system, long-term care in healthcare institutions and home settings has become essential for older adults with disabilities. However, the diverse and scattered care requirem...
With the development of information and communication technology, it has become possible to improve pharmacy management system (PMS) using these technologies. Our study aims to enhance the accuracy of drug attribute classification and recommend appro...
Accurate sample classification using transcriptomics data is crucial for advancing personalized medicine. Achieving this goal necessitates determining a suitable sample size that ensures adequate classification accuracy without undue resource allocat...
Diabetes mellitus is a complex metabolic disorder and one of the fastest-growing global public health concerns. The gut microbiota is implicated in the pathophysiology of various diseases, including diabetes. This study utilized 16S rRNA metagenomic ...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVE: Extracting PICO elements-Participants, Intervention, Comparison, and Outcomes-from clinical trial literature is essential for clinical evidence retrieval, appraisal, and synthesis. Existing approaches do not distinguish the attributes of P...
MOTIVATION: Identifying effective therapeutic targets poses a challenge in drug discovery, especially for uncharacterized diseases without known therapeutic targets (e.g. rare diseases, intractable diseases).
BACKGROUND: The high heterogeneity of Parkinson's disease (PD) hinders personalized interventions. Brain structure reflects damage and neuroplasticity and is one of the biological bases of symptomatology. Subtyping PD in the framework of brain struct...
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