The prediction of peptide-protein or protein-protein interactions (PPI) is a challenging task, especially if amino acid sequences are the only information available. Machine learning methods allow us to exploit the information content in PPI datasets...
AIM: Pancreatic cancer is one of the worst malignant tumors in prognosis. Therefore, to reduce the mortality rate of pancreatic cancer, early diagnosis and prompt treatment are particularly important.
This paper formulates a support vector machine with quantile hyper-spheres (QHSVM) for pattern classification. The idea of QHSVM is to build two quantile hyper-spheres with the same center for positive or negative training samples. Every quantile hyp...
IEEE journal of biomedical and health informatics
Feb 13, 2019
The diagnosis of type 2 diabetes (T2D) at an early stage has a key role for an adequate T2D integrated management system and patient's follow-up. Recent years have witnessed an increasing amount of available electronic health record (EHR) data and ma...
As is eminent, lung cancer is one of the death frightening syndromes among people in present cases. The earlier diagnosis and treatment of lung cancer can increase the endurance rate of the affected people. But, the structure of the cancer cell makes...
International journal of neural systems
Feb 8, 2019
Although electroconvulsive therapy (ECT) is one of the most effective treatments for major depressive disorder (MDD), the mechanism underlying the therapeutic efficacy and side effects of ECT remains poorly understood. Here, we investigated alteratio...
Genomic selection is revolutionizing plant breeding. However, still lacking are better statistical models for ordinal phenotypes to improve the accuracy of the selection of candidate genotypes. For this reason, in this paper we explore the genomic ba...
The significant role of microRNAs (miRNAs) in various biological processes and diseases has been widely studied and reported in recent years. Several computational methods associated with mature miRNA identification suffer various limitations involvi...
Computational intelligence and neuroscience
Feb 3, 2019
Gearboxes are mechanical devices that play an essential role in several applications, e.g., the transmission of automotive vehicles. Their malfunctioning may result in economic losses and accidents, among others. The rise of powerful graphical proces...
Computer methods and programs in biomedicine
Feb 1, 2019
BACKGROUND AND OBJECTIVE: Healthcare tweets are particularly challenging due to its sparse layout and its limited character size. Compared to previous method based on "bag of words" (BOW) model, this study uniquely identifies the enrichment protocol ...
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