AIMC Topic: Tissue Engineering

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Optimized Repopulation of Tendon Hydrogel: Synergistic Effects of Growth Factor Combinations and Adipose-Derived Stem Cells.

Hand (New York, N.Y.)
Tendon-derived extracellular matrix (ECM) hydrogel has been shown to augment tendon healing in vivo. We hypothesized that reseeding of the gel with adipose-derived stem cells (ASCs) could further assist repopulation of the gel and that combinations ...

Coefficient of Friction Patterns Can Identify Damage in Native and Engineered Cartilage Subjected to Frictional-Shear Stress.

Annals of biomedical engineering
The mechanical loading environment encountered by articular cartilage in situ makes frictional-shear testing an invaluable technique for assessing engineered cartilage. Despite the important information that is gained from this testing, it remains un...

Non-destructive assessment of tissue engineered cartilage maturity using visible and near infrared spectroscopy combined with machine learning.

Biosensors & bioelectronics
Tissue engineering is a promising approach to address the unmet clinical need for treating cartilage damage. Monitoring the characteristics of tissue-engineered cartilage constructs (TECs) during culture is critical for optimizing culture conditions ...

Beyond 3D Printing: How AI is Shaping the Future of Craniomaxillofacial Bone Tissue Engineering.

ACS biomaterials science & engineering
This perspective focuses on the potential of artificial intelligence (AI) in craniomaxillofacial (CMF) bone tissue engineering, mitigating current challenges, and driving the development of tailored biomaterials and clinical translation. CMF bone tis...

Comparative analysis of deep learning models for predicting biocompatibility in tissue scaffold images.

Computers in biology and medicine
MOTIVATION: Bioprinting enables the creation of complex tissue scaffolds, which are vital for tissue engineering. However, predicting scaffold biocompatibility before fabrication remains a critical challenge, potentially leading to inefficiencies and...

What insights can spatiotemporal esophageal atlases and deep learning bring to engineering the esophageal mucosa?

Developmental cell
In this issue of Developmental Cell, Yang et al. present an integrated experimental and computational platform that maps the spatiotemporal development of the human esophagus and predicts key signaling pathways governing epithelial differentiation. T...

3D Bioprinting Skin Equivalents: A Methodological Perspective on Human Keratinocyte and Fibroblast Models for Wound Repair and Regeneration.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Three-dimensional (3D) bioprinting is a promising approach to developing reliable tissue substitutes for translational research. The great interest in creating skin substitutes still faces challenges considering its structural and cellular complexity...

Recent advances in artificial intelligent strategies for tissue engineering and regenerative medicine.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
BACKGROUND: Tissue engineering and regenerative medicine (TERM) aim to repair or replace damaged or lost tissues or organs due to accidents, diseases, or aging, by applying different sciences. For this purpose, an essential part of TERM is the design...

Biofabrication of Living Actuators.

Annual review of biomedical engineering
The impact of tissue engineering has extended beyond a traditional focus in medicine to the rapidly growing realm of biohybrid robotics. Leveraging living actuators as functional components in machines has been a central focus of this field, generati...

Design optimization of geometrically confined cardiac organoids enabled by machine learning techniques.

Cell reports methods
Stem cell organoids are powerful models for studying organ development, disease modeling, drug screening, and regenerative medicine applications. The convergence of organoid technology, tissue engineering, and artificial intelligence (AI) could poten...