Spatially resolved transcriptomics enables mapping of multiplexed gene expression within tissue contexts. While existing methods prioritize spatially variable genes within a single slice, few address identifying genes with differential spatial expres...
OBJECTIVE: This study aims to establish a machine learning prediction model to explore the correlation between contrast-enhanced mammography (CEM) imaging features and molecular subtypes of mass-type breast cancer.
Despite advances in precision oncology, developing effective cancer therapeutics remains a significant challenge due to tumor heterogeneity and the limited availability of well-defined drug targets. Recent progress in generative artificial intelligen...
To develop and validate a machine learning-based prediction model to predict axillary lymph node (ALN) metastasis in triple negative breast cancer (TNBC) patients using magnetic resonance imaging (MRI) and clinical characteristics. This retrospective...
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants with widespread use and bioaccumulative potential. Short-chain PFAS such as perfluorohexanoic acid (PFHxA) and perfluorohexane sulfonate (PFHxS) have been introduced...
BACKGROUND AND PURPOSE: Radiomics analysis has emerged as a promising approach to aid in cancer diagnosis and treatment. However, radiomics research currently lacks standardization, and radiomics features can be highly dependent on acquisition and pr...
OBJECTIVE: To investigate whether digital mammography (DM) with artificial intelligence-based computer-aided diagnosis (AI-CAD) predicts pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) in human epidermal growth factor receptor...
Triple-Negative Breast Cancer (TNBC) is a highly aggressive subtype of breast cancer (BC) characterized by the absence of estrogen, progesterone, and HER2 receptors, resulting in limited therapeutic options. This article critically examines the role ...
OBJECTIVE: This study aimed to evaluate the predictive value of implementing machine learning models based on ultrasound radiomics and clinicopathological features in the survival analysis of triple-negative breast cancer (TNBC) patients.
INTRODUCTION: Breast cancer (BC) is the most prevalent malignant tumor in women, with triple-negative breast cancer (TNBC) showing the poorest prognosis among all subtypes. Glycosylation is increasingly recognized as a critical biomarker in the tumor...
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