AIMC Topic: Vaccination
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Estimation of the Basic Reproduction Number and Vaccination Coverage of Influenza in the United States (2017-18).
Journal of research in health sciences
Sep 22, 2018
BACKGROUND: Determining the epidemic threshold parameter helps health providers calculate the coverage while guiding them in planning the process of vaccination strategy. Since the trend and mechanism of influenza is very similar in different countri...
Haemophilus influenzae type b (Hib) seroprevalence and current epidemiology in England and Wales.
The Journal of infection
Dec 28, 2017
INTRODUCTION: The implementation of the Hib conjugate vaccine in the United Kingdom in 1992 resulted in a rapid decline in invasive Hib disease across all age groups. However, a resurgence in 2000-2002 prompted the introduction of additional control ...
Wales
Cohort Studies
Infant
Haemophilus Infections
Haemophilus Vaccines
Humans
Child, Preschool
Seroepidemiologic Studies
Haemophilus influenzae type b
Prevalence
United Kingdom
Child
Immunization, Secondary
Immunoglobulin G
Adolescent
Vaccination
Antibodies, Bacterial
Female
Vaccines, Conjugate
Risk Factors
Male
Randomized clinical trial of a single versus a double dose of 13-valent pneumococcal conjugate vaccine in adults 55 through 74 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine.
Vaccine
Dec 24, 2017
INTRODUCTION: In older adults, prior administration of 23-valent pneumococcal polysaccharide vaccine (PPSV23) blunts the opsonophagocytic antibody (OPA) response to subsequent administration of 13-valent pneumococcal conjugate vaccine (PCV13). To det...
Immunologic non-inferiority and safety of the investigational pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) 4-dose vial presentation compared to the licensed PHiD-CV 1-dose vial presentation in infants: A phase III randomized study.
Vaccine
Dec 23, 2017
BACKGROUND: To support vaccination programs in developing countries, a 4-dose vial presentation of pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was developed. This study assessed immunologic non-inferiority a...
A fuzzy MICMAC analysis for improving supply chain performance of basic vaccines in developing countries.
Expert review of vaccines
Nov 15, 2017
INTRODUCTION: In recent years, demand to improve child immunization coverage globally, and the development of the latest vaccines and technology has made the vaccine market very complex. The rise in such complexities often gives birth to numerous iss...
Leveraging machine learning-based approaches to assess human papillomavirus vaccination sentiment trends with Twitter data.
BMC medical informatics and decision making
Jul 5, 2017
BACKGROUND: As one of the serious public health issues, vaccination refusal has been attracting more and more attention, especially for newly approved human papillomavirus (HPV) vaccines. Understanding public opinion towards HPV vaccines, especially ...
An inactivated influenza D virus vaccine partially protects cattle from respiratory disease caused by homologous challenge.
Veterinary microbiology
Dec 21, 2016
Originally isolated from swine, the proposed influenza D virus has since been shown to be common in cattle. Inoculation of IDV to naïve calves resulted in mild respiratory disease histologically characterized by tracheitis. As several studies have as...
An informed deep learning model of the Omicron wave and the impact of vaccination.
Computers in biology and medicine
Jun 1, 2025
The Omicron (B.1.1.529) variant of SARS-CoV-2 emerged in November 2021 and has since evolved into multiple lineages. Understanding its transmission, vaccine efficacy, and potential for reinfection is crucial. This study examines the dynamics of Omicr...
An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study.
Science translational medicine
May 14, 2025
There are currently no licensed vaccines for norovirus, a leading cause of epidemic and endemic gastroenteritis worldwide. Clinical advancement of promising vaccine candidates from phase 2 studies to phase 3 field trials has been hampered by the lack...
TWINVAX: conceptual model of a digital twin for immunisation services in primary health care.
Frontiers in public health
Jan 1, 2025
INTRODUCTION: This paper presents a proposal for the modelling and reference architecture of a digital twin for immunisation services in primary health care centres. The system leverages Industry 4.0 concepts and technologies, such as the Internet of...
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