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White Matter

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Grade prediction of lesions in cerebral white matter using a convolutional neural network.

PloS one
We established a diagnostic method for cerebral white matter lesions using MRI images and examined the relationship between the MRI images and the medical checkup data. There were approximately 25 MRI images for each patient's head, from the top of t...

On the application of hybrid deep 3D convolutional neural network algorithms for predicting the micromechanics of brain white matter.

Computer methods and programs in biomedicine
BACKGROUND: Material characterization of brain white matter (BWM) is difficult due to the anisotropy inherent to the three-dimensional microstructure and the various interactions between heterogeneous brain-tissue (axon, myelin, and glia). Developing...

Deep learning for efficient reconstruction of highly accelerated 3D FLAIR MRI in neurological deficits.

Magma (New York, N.Y.)
OBJECTIVE: To compare compressed sensing (CS) and the Cascades of Independently Recurrent Inference Machines (CIRIM) with respect to image quality and reconstruction times when 12-fold accelerated scans of patients with neurological deficits are reco...

Accurate low and high grade glioma classification using free water eliminated diffusion tensor metrics and ensemble machine learning.

Scientific reports
Glioma, a predominant type of brain tumor, can be fatal. This necessitates an early diagnosis and effective treatment strategies. Current diagnosis is based on biopsy, prompting the need for non invasive neuroimaging alternatives. Diffusion tensor im...

Deep learning-based segmentation in MRI-(immuno)histological examination of myelin and axonal damage in normal-appearing white matter and white matter hyperintensities.

Brain pathology (Zurich, Switzerland)
The major vascular cause of dementia is cerebral small vessel disease (SVD). Its diagnosis relies on imaging hallmarks, such as white matter hyperintensities (WMH). WMH present a heterogenous pathology, including myelin and axonal loss. Yet, these mi...

Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases.

Acta neuropathologica communications
Accurate and scalable quantification of amyloid-β (Aβ) pathology is crucial for deeper disease phenotyping and furthering research in Alzheimer Disease (AD). This multidisciplinary study addresses the current limitations on neuropathology by leveragi...

Accelerating FLAIR imaging via deep learning reconstruction: potential for evaluating white matter hyperintensities.

Japanese journal of radiology
PURPOSE: To evaluate deep learning-reconstructed (DLR)-fluid-attenuated inversion recovery (FLAIR) images generated from undersampled data, compare them with fully sampled and rapidly acquired FLAIR images, and assess their potential for white matter...

Structural-based uncertainty in deep learning across anatomical scales: Analysis in white matter lesion segmentation.

Computers in biology and medicine
This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of multiple sclerosi...

Evaluating retinal blood vessels for predicting white matter hyperintensities in ischemic stroke: A deep learning approach.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVE: This study aims to investigate whether a deep learning approach incorporating retinal blood vessels can effectively identify ischemic stroke patients with a high burden of White Matter Hyperintensities (WMH) using Nuclear Magnetic Resonanc...

Automated Quantification of Cerebral Microbleeds in SWI: Association with Vascular Risk Factors, White Matter Hyperintensity Burden, and Cognitive Function.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: The amount and distribution of cerebral microbleeds (CMB) are important risk factors for cognitive impairment. Our objective was to train and validate a deep learning (DL)-based segmentation model for cerebral microbleeds (CMB...