Automated computer-aided detection (CADe) has been an important tool in clinical practice and research. State-of-the-art methods often show high sensitivities at the cost of high false-positives (FP) per patient rates. We design a two-tiered coarse-t...
Computer-aided image analysis of histopathology specimens could potentially provide support for early detection and improved characterization of diseases such as brain tumor, pancreatic neuroendocrine tumor (NET), and breast cancer. Automated nucleus...
The imaging performance of fluorescence molecular tomography (FMT) improves when information from the underlying anatomy is incorporated into the inversion scheme, in the form of priors. The requirement for incorporation of priors has recently driven...
Cardiac Phase-resolved Blood-Oxygen-Level Dependent (CP-BOLD) MRI provides a unique opportunity to image an ongoing ischemia at rest. However, it requires post-processing to evaluate the extent of ischemia. To address this, here we propose an unsuper...
Patient-specific blood flow modeling combining imaging data and computational fluid dynamics can aid in the assessment of coronary artery disease. Accurate coronary segmentation and realistic physiologic modeling of boundary conditions are important ...
In this paper we present a compressed sensing (CS) method adapted to 3D ultrasound imaging (US). In contrast to previous work, we propose a new approach based on the use of learned overcomplete dictionaries that allow for much sparser representations...
Recent achievement of the learning-based classification leads to the noticeable performance improvement in automatic polyp detection. Here, building large good datasets is very crucial for learning a reliable detector. However, it is practically chal...
Task-based fMRI (tfMRI) has been widely used to explore functional brain networks via predefined stimulus paradigm in the fMRI scan. Traditionally, the general linear model (GLM) has been a dominant approach to detect task-evoked networks. However, G...
Conventional image restoration algorithms use transform-domain filters, which separate the noise from the sparse signal among the transform components or apply spatial smoothing filters in real space whose design relies on prior assumptions about the...
Efficient and accurate segmentation of cellular structures in microscopic data is an essential task in medical imaging. Many state-of-the-art approaches to image segmentation use structured models whose parameters must be carefully chosen for optimal...
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