Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Jan 24, 2025
PURPOSE: Establishing an accurate prognosis remains challenging in older patients with cancer because of the population's heterogeneity and the current predictive models' reduced ability to capture the complex interactions between oncologic and geria...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Jul 31, 2024
PURPOSE: Cancers with homologous recombination deficiency (HRD) can benefit from platinum salts and poly(ADP-ribose) polymerase inhibitors. Standard diagnostic tests for detecting HRD require molecular profiling, which is not universally available.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Jun 6, 2024
PURPOSE: Artificial intelligence can reduce the time used by physicians on radiological assessments. For F-fluorodeoxyglucose-avid lymphomas, obtaining complete metabolic response (CMR) by end of treatment is prognostic.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Feb 15, 2024
PURPOSE: For patients with advanced cancer, early consultations with palliative care (PC) specialists reduce costs, improve quality of life, and prolong survival. However, capacity limitations prevent all patients from receiving PC shortly after diag...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Feb 5, 2024
PURPOSE: A combination of fluorouracil, leucovorin, and oxaliplatin (FOLFOX) is the standard for adjuvant therapy of resected early-stage colon cancer (CC). Oxaliplatin leads to lasting and disabling neurotoxicity. Reserving the regimen for patients ...