Tumor-infiltrating lymphocytes (TILs) are capable of recognizing tumor antigens, impacting tumor prognosis, predicting the efficacy of neoadjuvant therapies, contributing to the development of new cell-based immunotherapies, studying the tumor immune...
Whole slide images (WSI), due to their gigabyte-scale size and ultra-high resolution, play a significant role in diagnostic pathology. However, the enormous data size makes it difficult to directly input these images into image processing units (GPU)...
Prostate cancer is a prevalent male malignancy, with increasing incidence rates placing significant diagnostic burdens on pathology services worldwide. Artificial intelligence (AI) is emerging as a promising aid in enhancing diagnostic efficiency and...
CONTEXT: Staging cancer patients is crucial and requires analyzing all removed lymph nodes microscopically for metastasis. For this pivotal task, convolutional neural networks (CNN) can reduce workload and improve diagnostic accuracy.
OBJECTIVE: Construct a prediction model for lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) using Probe Electrospray Ionization Mass Spectrometry (PESI - MS) combined with artificial intelligence (AI), to assist in the preoperative p...
Breast cancer is a significant global health concern, where precise identification of proteins like Human Epidermal Growth Factor Receptor 2 (HER2) in cancer cells via Immunohistochemistry (IHC) is pivotal for treatment decisions. HER2 overexpression...
Our study investigated the predictive efficacy of AI-based Machine Learning (ML) model for determining HER2 status in a population of 3424 breast cancer patients. Multivariate logistic regression analysis identified several independent variables that...
BACKGROUND: Ovarian cancer (OC), owing to its substantial heterogeneity and high invasiveness, has historically been devoid of precise, individualized treatment options. This study aimed to establish integrated consensus subtypes of OC using differen...
BACKGROUND: Prognostic histopathological features such as mitosis in melanoma are excluded from the staging systems due to inter-observer variability and time constraints. While digital pathology offers artificial intelligence-driven solutions, exist...
Diseases that develop necrotizing vasculitis of cutaneous muscular arteries include cutaneous arteritis (CA) and polyarteritis nodosa (PAN). It is difficult to distinguish them based on skin biopsy findings alone. This study demonstrated that artific...