AIMC Topic: Acute Coronary Syndrome

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Machine-learned models using hematological inflammation markers in the prediction of short-term acute coronary syndrome outcomes.

Journal of translational medicine
BACKGROUND: Increased systemic and local inflammation play a vital role in the pathophysiology of acute coronary syndrome. This study aimed to assess the usefulness of selected machine learning methods and hematological markers of inflammation in pre...

Adversarial MACE Prediction After Acute Coronary Syndrome Using Electronic Health Records.

IEEE journal of biomedical and health informatics
Acute coronary syndrome (ACS), as an emergent and severe syndrome due to decreased blood flow in the coronary arteries, is a leading cause of death and serious long-term disability globally. ACS is usually caused by one of three problems: ST elevatio...

Simulation of patient flow in multiple healthcare units using process and data mining techniques for model identification.

Journal of biomedical informatics
INTRODUCTION: An approach to building a hybrid simulation of patient flow is introduced with a combination of data-driven methods for automation of model identification. The approach is described with a conceptual framework and basic methods for comb...

The effect of fasting status on lipids, lipoproteins, and inflammatory biomarkers assessed after hospitalization for an acute coronary syndrome: Insights from PROVE IT-TIMI 22.

Clinical cardiology
BACKGROUND: For decades, fasting for 8 to 12 hours has been recommended for measurement of lipid profiles. The effect of fasting on low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) has been described in healthy cohorts and those wit...

Indoleamine 2,3-Dioxygenase (IDO) Enzyme Links Innate Immunity and Altered T-Cell Differentiation in Non-ST Segment Elevation Acute Coronary Syndrome.

International journal of molecular sciences
Atherosclerosis is a chronic inflammatory disease characterized by a complex interplay between innate and adaptive immunity. Dendritic cells (DCs) play a key role in T-cell activation and regulation by promoting a tolerogenic environment through the ...

Machine Learning Improves Risk Stratification After Acute Coronary Syndrome.

Scientific reports
The accurate assessment of a patient's risk of adverse events remains a mainstay of clinical care. Commonly used risk metrics have been based on logistic regression models that incorporate aspects of the medical history, presenting signs and symptoms...

Coronary Computed Tomographic Angiography-Derived Fractional Flow Reserve Based on Machine Learning for Risk Stratification of Non-Culprit Coronary Narrowings in Patients with Acute Coronary Syndrome.

The American journal of cardiology
This study investigated the prognostic value of coronary computed tomography angiography (cCTA)-derived fractional flow reserve (CT-FFR) in patients with acute coronary syndrome (ACS) and multivessel disease to gauge significance and guide management...

A Regularized Deep Learning Approach for Clinical Risk Prediction of Acute Coronary Syndrome Using Electronic Health Records.

IEEE transactions on bio-medical engineering
OBJECTIVE: Acute coronary syndrome (ACS), as a common and severe cardiovascular disease, is a leading cause of death and the principal cause of serious long-term disability globally. Clinical risk prediction of ACS is important for early intervention...

[Intelligent systems tools in the diagnosis of acute coronary syndromes: A systemic review].

Archivos de cardiologia de Mexico
BACKGROUND: Acute myocardial infarction is the leading cause of non-communicable deaths worldwide. Its diagnosis is a highly complex task, for which modelling through automated methods has been attempted. A systematic review of the literature was per...

Prediction of high on-treatment platelet reactivity in clopidogrel-treated patients with acute coronary syndromes.

International journal of cardiology
BACKGROUND: About 40% of clopidogrel-treated patients display high platelet reactivity (HPR). Alternative treatments of HPR patients, identified by platelet function tests, failed to improve their clinical outcomes in large randomized clinical trials...