AIMC Topic: Adult

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Survival outcome prediction in cervical cancer: Cox models vs deep-learning model.

American journal of obstetrics and gynecology
BACKGROUND: Historically, the Cox proportional hazard regression model has been the mainstay for survival analyses in oncologic research. The Cox proportional hazard regression model generally is used based on an assumption of linear association. How...

HIV is associated with endothelial activation despite ART, in a sub-Saharan African setting.

Neurology(R) neuroimmunology & neuroinflammation
OBJECTIVE: To study the relationship between endothelial dysfunction, HIV infection, and stroke in Malawians.

Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images: a retrospective, multicohort, diagnostic study.

The Lancet. Oncology
BACKGROUND: The incidence of thyroid cancer is rising steadily because of overdiagnosis and overtreatment conferred by widespread use of sensitive imaging techniques for screening. This overall incidence growth is especially driven by increased diagn...

Retrospective Data Analysis of the Influence of Age and Sex on TPMT Activity and Its Phenotype-Genotype Correlation.

The journal of applied laboratory medicine
BACKGROUND: Therapeutic efficacy and toxicity of thiopurine drugs (used as anticancer and immunosuppressant agents) are affected by thiopurine S-methyltransferase (TPMT) enzyme activity. genotype and/or phenotype is used to predict the risk for adve...

Deep Learning-Based Detection of Intracranial Aneurysms in 3D TOF-MRA.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: The rupture of an intracranial aneurysm is a serious incident, causing subarachnoid hemorrhage associated with high fatality and morbidity rates. Because the demand for radiologic examinations is steadily growing, physician fa...

MRI-compatible pneumatic stimulator for sensorimotor mapping.

Journal of neuroscience methods
BACKGROUND: Two major concerns with respect to task-based motor functional magnetic resonance imaging (fMRI) are inadequate participants' performance as well as intra- and inter-subject variability in execution of the motor action.

Fibroblast growth factor 21 association with subclinical atherosclerosis and arterial stiffness in type 2 diabetes.

Diabetes & metabolic syndrome
AIM: To evaluate the association of serum FGF21 with subclinical atherosclerosis and pulse wave velocity, a marker of arterial stiffness, in type 2 diabetes Egyptian patients.

Swall-E: A robotic in-vitro simulation of human swallowing.

PloS one
Swallowing is a complex physiological function that can be studied through medical imagery techniques such as videofluoroscopy (VFS), dynamic magnetic resonance imagery (MRI) and fiberoptic endoscopic evaluation of swallowing (FEES). VFS is the gold ...

Automated detection of erythema migrans and other confounding skin lesions via deep learning.

Computers in biology and medicine
Lyme disease can lead to neurological, cardiac, and rheumatologic complications when untreated. Timely recognition of the erythema migrans rash of acute Lyme disease by patients and clinicians is crucial to early diagnosis and treatment. Our objectiv...

A convolutional neural network Cascade for plantar pressure images registration.

Gait & posture
BACKGROUND: Plantar pressure image (PPI) recorded in high spatial and temporal resolution is very useful in clinical gait analysis. For functional analysis of PPI, image registration is often performed to maximally correlate source image with a templ...