AIMC Topic: Aged

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Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease.

The Journal of clinical investigation
BACKGROUNDCeramides are sphingolipids that play causative roles in diabetes and heart disease, with their serum levels measured clinically as biomarkers of cardiovascular disease (CVD).METHODSWe performed targeted lipidomics on serum samples from ind...

Application of Convolutional Neural Networks for Detection of Superficial Nonampullary Duodenal Epithelial Tumors in Esophagogastroduodenoscopic Images.

Clinical and translational gastroenterology
OBJECTIVES: A superficial nonampullary duodenal epithelial tumor (SNADET) is defined as a mucosal or submucosal sporadic tumor of the duodenum that does not arise from the papilla of Vater. SNADETs rarely metastasize to the lymph nodes, and most can ...

Machine Learning and Mechanistic Modeling for Prediction of Metastatic Relapse in Early-Stage Breast Cancer.

JCO clinical cancer informatics
PURPOSE: For patients with early-stage breast cancer, predicting the risk of metastatic relapse is of crucial importance. Existing predictive models rely on agnostic survival analysis statistical tools (eg, Cox regression). Here we define and evaluat...

Low-Dose Abdominal CT Using a Deep Learning-Based Denoising Algorithm: A Comparison with CT Reconstructed with Filtered Back Projection or Iterative Reconstruction Algorithm.

Korean journal of radiology
OBJECTIVE: To compare the image quality of low-dose (LD) computed tomography (CT) obtained using a deep learning-based denoising algorithm (DLA) with LD CT images reconstructed with a filtered back projection (FBP) and advanced modeled iterative reco...

Temporal convolutional networks allow early prediction of events in critical care.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Clinical interventions and death in the intensive care unit (ICU) depend on complex patterns in patients' longitudinal data. We aim to anticipate these events earlier and more consistently so that staff can consider preemptive action.

Neuropsychiatric symptoms as predictors of conversion from MCI to dementia: a machine learning approach.

International psychogeriatrics
OBJECTIVES: To use a Machine Learning (ML) approach to compare Neuropsychiatric Symptoms (NPS) in participants of a longitudinal study who developed dementia and those who did not.

Classification Techniques for Cardio-Vascular Diseases Using Supervised Machine Learning.

Medical archives (Sarajevo, Bosnia and Herzegovina)
INTRODUCTION: The World Health Organization has estimated that 12 million deaths occur worldwide, every year due to Heart diseases. Half the deaths in the developed countries are due to cardiovascular diseases. The early prognosis of cardiovascular d...

Identification of prognostic immune-related signature predicting the overall survival for colorectal cancer.

European review for medical and pharmacological sciences
OBJECTIVE: The morbidity and mortality of patients with colorectal cancer, one of the most common malignant tumors worldwide, is steadily increasing. The aim of this study was to investigate the association between prognostic immune-related gene prof...