AIMC Topic: Aged

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Association of and gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population.

Frontiers in immunology
INTRODUCTION: Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. Although RA is chiefly associated with HLA class II, nevertheless some HLA class I associations have also been observed. These molecules present...

Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post three-dose primary series in adults with inborn errors of immunity and their breakthrough infections.

Frontiers in immunology
PURPOSE: Many individuals with inborn errors of immunity (IEIs) have poor humoral immune (HI) vaccine responses. Only a few studies have examined specific cell-mediated immune (CMI) responses to coronavirus disease 2019 (COVID-19) vaccines in this po...

A Machine Learning Model for Predicting the HER2 Positive Expression of Breast Cancer Based on Clinicopathological and Imaging Features.

Academic radiology
RATIONALE AND OBJECTIVES: To develop a machine learning (ML) model based on clinicopathological and imaging features to predict the Human Epidermal Growth Factor Receptor 2 (HER2) positive expression (HER2-p) of breast cancer (BC), and to compare its...

Motion-Compensated Multishot Pancreatic Diffusion-Weighted Imaging With Deep Learning-Based Denoising.

Investigative radiology
OBJECTIVES: Pancreatic diffusion-weighted imaging (DWI) has numerous clinical applications, but conventional single-shot methods suffer from off resonance-induced artifacts like distortion and blurring while cardiovascular motion-induced phase incons...

Do people prefer AI-generated patient educational materials over traditional ones?

Patient education and counseling
OBJECTIVE: This study aimed to assess people's preference between traditional and Artificial Intelligence (AI)-generated colon cancer staging Patient Education Materials (PEMs).

Predicting doxorubicin-induced cardiotoxicity in breast cancer: leveraging machine learning with synthetic data.

Medical & biological engineering & computing
Doxorubicin (DOXO) is a primary treatment for breast cancer but can cause cardiotoxicity in over 25% of patients within the first year post-chemotherapy. Recognizing at-risk patients before DOXO initiation offers pathways for alternative treatments o...

Diagnostic accuracy of an automated classifier for the detection of pleural effusions in patients undergoing lung ultrasound.

The American journal of emergency medicine
RATIONALE: Lung ultrasound, the most precise diagnostic tool for pleural effusions, is underutilized due to healthcare providers' limited proficiency. To address this, deep learning models can be trained to recognize pleural effusions. However, curre...

Deep learning-based MVIT-MLKA model for accurate classification of pancreatic lesions: a multicenter retrospective cohort study.

La Radiologia medica
BACKGROUND: Accurate differentiation between benign and malignant pancreatic lesions is critical for effective patient management. This study aimed to develop and validate a novel deep learning network using baseline computed tomography (CT) images t...

Opportunistic AI for enhanced cardiovascular disease risk stratification using abdominal CT scans.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
This study introduces the Deep Learning-based Cardiovascular Disease Incident (DL-CVDi) score, a novel biomarker derived from routine abdominal CT scans, optimized to predict cardiovascular disease (CVD) risk using deep survival learning. CT imaging,...

Research on predicting radiographic exposure time in imaging based on neural network prediction models.

Clinical neurology and neurosurgery
OBJECTIVE: To explore the anatomical and clinical factors that affect the radiographic exposure time in radial artery cerebral angiography and to establish a model.