AIMC Topic: Aged

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Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis.

Cell reports. Medicine
Clinical studies investigating the benefits of beta-lactam therapeutic drug monitoring (TDM) among critically ill patients are hindered by small patient groups, variability between studies, patient heterogeneity, and inadequate use of TDM. Accordingl...

Admission blood tests predicting survival of SARS-CoV-2 infected patients: a practical implementation of graph convolution network in imbalance dataset.

BMC infectious diseases
BACKGROUND: Predicting an individual's risk of death from COVID-19 is essential for planning and optimising resources. However, since the real-world mortality rate is relatively low, particularly in places like Hong Kong, this makes building an accur...

A Deep Learning Approach to Predict Recanalization First-Pass Effect following Mechanical Thrombectomy in Patients with Acute Ischemic Stroke.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Following endovascular thrombectomy in patients with large-vessel occlusion stroke, successful recanalization from 1 attempt, known as the first-pass effect, has correlated favorably with long-term outcomes. Pretreatment imagi...

A Parkinson's Auxiliary Diagnosis Algorithm Based on a Hyperparameter Optimization Method of Deep Learning.

IEEE/ACM transactions on computational biology and bioinformatics
Parkinson's disease is a common mental disease in the world, especially in the middle-aged and elderly groups. Today, clinical diagnosis is the main diagnostic method of Parkinson's disease, but the diagnosis results are not ideal, especially in the ...

Impact of training data composition on the generalizability of convolutional neural network aortic cross-section segmentation in four-dimensional magnetic resonance flow imaging.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
BACKGROUND: Four-dimensional cardiovascular magnetic resonance flow imaging (4D flow CMR) plays an important role in assessing cardiovascular diseases. However, the manual or semi-automatic segmentation of aortic vessel boundaries in 4D flow data int...

Combining Image Similarity and Predictive Artificial Intelligence Models to Decrease Subjectivity in Thyroid Nodule Diagnosis and Improve Malignancy Prediction.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
OBJECTIVES: To evaluate the efficacy of combining predictive artificial intelligence (AI) and image similarity model to risk stratify thyroid nodules, using retrospective external validation study.

EasyPISA: Automatic Integrated PISA Measurements of Mitral Regurgitation From 2-D Color-Doppler Using Deep Learning.

Ultrasound in medicine & biology
OBJECTIVE: The proximal isovelocity surface area (PISA) method is a well-established approach for mitral regurgitation (MR) quantification. However, it exhibits high inter-observer variability and inaccuracies in cases of non-hemispherical flow conve...

TS-AI: A deep learning pipeline for multimodal subject-specific parcellation with task contrasts synthesis.

Medical image analysis
Accurate mapping of brain functional subregions at an individual level is crucial. Task-based functional MRI (tfMRI) captures subject-specific activation patterns during various functions and behaviors, facilitating the individual localization of fun...

Significance of plasma p-tau217 in predicting long-term dementia risk in older community residents: Insights from machine learning approaches.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Whether plasma biomarkers play roles in predicting incident dementia among the general population is worth exploring.

Feasibility of Adjunct Therapy with a Robotic Hand Orthosis after Botulinum Toxin Injections in Persons with Spasticity: A Pilot Study.

Toxins
Upper-limb spasticity, frequent after central nervous system lesions, is typically treated with botulinum neurotoxin type A (BoNT-A) injections to reduce muscle tone and increase range of motion. However, performing adjunct physical therapy post-BoNT...