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An integrated analytical approach for biomarker discovery in esophageal cancer: Combining trace element and oxidative stress profiling with machine learning.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
May 28, 2025
BACKGROUND: Early detection of esophageal squamous cell carcinoma (ESCC) significantly improves survival rates, yet reliable biochemical biomarkers for early diagnosis remain limited. The aim of this study is to identify potential early diagnostic bi...
Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical features.
EBioMedicine
May 28, 2025
BACKGROUND: Ductal Carcinoma In Situ (DCIS) can progress to ipsilateral invasive breast cancer (IBC) but over 75% of DCIS lesions do not progress if untreated. Currently, DCIS that might progress to IBC cannot reliably be identified. Therefore, most ...
Detecting Tardive Dyskinesia Using Video-Based Artificial Intelligence.
The Journal of clinical psychiatry
May 28, 2025
Tardive dyskinesia (TD) is a late-onset adverse effect of dopamine receptor-blocking medications, characterized by involuntary movements primarily affecting the mouth, though other body parts may be involved. Severity of TD varies from mild to debil...
Operationalizing postmortem pathology-MRI association studies in Alzheimer's disease and related disorders with MRI-guided histology sampling.
Acta neuropathologica communications
May 28, 2025
Postmortem neuropathological examination, while the gold standard for diagnosing neurodegenerative diseases, often relies on limited regional sampling that may miss critical areas affected by Alzheimer's disease and related disorders. Ultra-high reso...
Personalized prediction of gait freezing using dynamic mode decomposition.
Scientific reports
May 28, 2025
Freezing of gait (FoG) is a common severe gait disorder in patients with advanced Parkinson's disease. The ability to predict the onset of FoG episodes early on allows for timely intervention, which is essential for improving the life quality of pati...
Improving ACS prediction in T2DM patients by addressing false records in electronic medical records using propensity score.
Scientific reports
May 28, 2025
Our study aims to improve the prediction performance of machine learning (ML) models by addressing false records (i.e., false positive, false negative, or missingness) in binary categorical variables in electronic medical records (EMRs) using propens...
MicroRNA signature predicts post operative atrial fibrillation after coronary artery bypass grafting.
Scientific reports
May 28, 2025
Early detection of atrial fibrillation (AFib) is crucial for altering its natural progression and complication profile. Traditional demographic and lifestyle factors often fail as predictors of AFib. This study investigated pre-operative, circulating...
C2 pars interarticularis length on the side of high-riding vertebral artery with implications for pars screw insertion.
Scientific reports
May 28, 2025
C2 pars interarticularis length (C2PIL) required for pars screws has not been thoroughly studied in subjects with high-riding vertebral artery (HRVA). We aimed to measure C2PIL specifically on the sides with HRVA, define short pars, optimal pars scre...
Advanced predictive modeling for enhanced mortality prediction in ICU stroke patients using clinical data.
PloS one
May 28, 2025
Background Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in intensive care u...
Hemoglobin - to - red cell distribution width ratio in depression symptoms: Threshold effects and metabolic - inflammatory mediation revealed by multimodal machine learning and symptom network analysis in 196,260 adults.
Journal of affective disorders
May 27, 2025
OBJECTIVE: To investigate the association between hemoglobin to red blood cell distribution width ratio (HRR) and depression symptoms.
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