AIMC Topic: Algorithms

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Machine Learning and Mechanistic Modeling for Prediction of Metastatic Relapse in Early-Stage Breast Cancer.

JCO clinical cancer informatics
PURPOSE: For patients with early-stage breast cancer, predicting the risk of metastatic relapse is of crucial importance. Existing predictive models rely on agnostic survival analysis statistical tools (eg, Cox regression). Here we define and evaluat...

Quantitative Assessment of the Effects of Compression on Deep Learning in Digital Pathology Image Analysis.

JCO clinical cancer informatics
PURPOSE: Deep learning (DL), a class of approaches involving self-learned discriminative features, is increasingly being applied to digital pathology (DP) images for tasks such as disease identification and segmentation of tissue primitives (eg, nucl...

Systematic Review of Privacy-Preserving Distributed Machine Learning From Federated Databases in Health Care.

JCO clinical cancer informatics
Big data for health care is one of the potential solutions to deal with the numerous challenges of health care, such as rising cost, aging population, precision medicine, universal health coverage, and the increase of noncommunicable diseases. Howeve...

Deep learning-based quantitative visualization and measurement of extraperitoneal hematoma volumes in patients with pelvic fractures: Potential role in personalized forecasting and decision support.

The journal of trauma and acute care surgery
INTRODUCTION: Admission computed tomography (CT) is a widely used diagnostic tool for patients with pelvic fractures. In this pilot study, we hypothesized that pelvic hematoma volumes derived using a rapid automated deep learning-based quantitative v...

medExtractR: A targeted, customizable approach to medication extraction from electronic health records.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: We developed medExtractR, a natural language processing system to extract medication information from clinical notes. Using a targeted approach, medExtractR focuses on individual drugs to facilitate creation of medication-specific research...

A combined strategy of feature selection and machine learning to identify predictors of prediabetes.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To identify predictors of prediabetes using feature selection and machine learning on a nationally representative sample of the US population.

iATC-NRAKEL: an efficient multi-label classifier for recognizing anatomical therapeutic chemical classes of drugs.

Bioinformatics (Oxford, England)
MOTIVATION: The anatomical therapeutic chemical (ATC) classification system plays an increasingly important role in drug repositioning and discovery. The correct identification of classes in each level of such system that a given drug may belong to i...