AIMC Topic: Alzheimer Disease

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Applying Automated MR-Based Diagnostic Methods to the Memory Clinic: A Prospective Study.

Journal of Alzheimer's disease : JAD
Several studies have demonstrated that fully automated pattern recognition methods applied to structural magnetic resonance imaging (MRI) aid in the diagnosis of dementia, but these conclusions are based on highly preselected samples that significant...

Use of Robotic Pets in Providing Stimulation for Nursing Home Residents with Dementia.

Studies in health technology and informatics
Trial experiments utilized robotic pets to facilitate self-reliance in nursing home residents. A remote-control robot modeled clear and meaningful behaviors to elderly residents. Special attention was paid to its effects on mental and social domains....

Epistasis analysis using artificial intelligence.

Methods in molecular biology (Clifton, N.J.)
Here we introduce artificial intelligence (AI) methodology for detecting and characterizing epistasis in genetic association studies. The ultimate goal of our AI strategy is to analyze genome-wide genetics data as a human would using sources of exper...

Defining multivariate normative rules for healthy aging using neuroimaging and machine learning: an application to Alzheimer's disease.

Journal of Alzheimer's disease : JAD
BACKGROUND: Neuroimaging techniques combined with computational neuroanatomy have been playing a role in the investigation of healthy aging and Alzheimer's disease (AD). The definition of normative rules for brain features is a crucial step to establ...

Factors associated with motor vehicle crashes in cognitively impaired older adults.

Alzheimer disease and associated disorders
Because cognitive impairment might pose a safety risk for these drivers and the public, we examined what patient characteristics might be associated with motor vehicle crashes, in a retrospective study of all new referrals to a geriatric clinic speci...