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Alzheimer Disease

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Criticality of Nursing Care for Patients With Alzheimer's Disease in the ICU: Insights From MIMIC III Dataset.

Clinical nursing research
Alzheimer's disease (AD) patients admitted to intensive care units (ICUs) exhibit varying survival outcomes due to the unique challenges in managing AD patients. Stratifying patient mortality risk and understanding the criticality of nursing care are...

A Novel Method to Identify Mild Cognitive Impairment Using Dynamic Spatio-Temporal Graph Neural Network.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Resting-state functional magnetic resonance imaging (rs-fMRI) has been widely used in the identification of mild cognitive impairment (MCI) research, MCI patients are relatively at a higher risk of progression to Alzheimer's disease (AD). However, al...

Comorbidity-based framework for Alzheimer's disease classification using graph neural networks.

Scientific reports
Alzheimer's disease (AD), the most prevalent form of dementia, requires early prediction for timely intervention. Current deep learning approaches, particularly those using traditional neural networks, face challenges such as handling high-dimensiona...

An efficient ranking-based ensembled multiclassifier for neurodegenerative diseases classification using deep learning.

Journal of neural transmission (Vienna, Austria : 1996)
Neurodegenerative diseases are group of debilitating and progressive disorders that primarily affect the structure and functions of nervous system, leading to gradual loss of neurons and subsequent decline in cognitive, and behavioral activities. The...

Classification of Alzheimer disease using DenseNet-201 based on deep transfer learning technique.

PloS one
Alzheimer's disease (AD) is a brain illness that causes gradual memory loss. AD has no treatment and cannot be cured, so early detection is critical. Various AD diagnosis approaches are used in this regard, but Magnetic Resonance Imaging (MRI) provid...

The application value of Rs-fMRI-based machine learning models for differentiating mild cognitive impairment from Alzheimer's disease: a systematic review and meta-analysis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
BACKGROUND: Various machine learning (ML) models based on resting-state functional MRI (Rs-fMRI) have been developed to facilitate differential diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease (AD). However, the diagnostic accurac...

Advancing Tau PET Quantification in Alzheimer Disease with Machine Learning: Introducing THETA, a Novel Tau Summary Measure.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Alzheimer disease (AD) exhibits spatially heterogeneous 3- or 4-repeat tau deposition across participants. Our overall goal was to develop an automated method to quantify the heterogeneous burden of tau deposition into a single number that would be c...

Cost-Sensitive Weighted Contrastive Learning Based on Graph Convolutional Networks for Imbalanced Alzheimer's Disease Staging.

IEEE transactions on medical imaging
Identifying the progression stages of Alzheimer's disease (AD) can be considered as an imbalanced multi-class classification problem in machine learning. It is challenging due to the class imbalance issue and the heterogeneity of the disease. Recentl...

Super-Resolving and Denoising 4D flow MRI of Neurofluids Using Physics-Guided Neural Networks.

Annals of biomedical engineering
PURPOSE: To obtain high-resolution velocity fields of cerebrospinal fluid (CSF) and cerebral blood flow by applying a physics-guided neural network (div-mDCSRN-Flow) to 4D flow MRI.

Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer's disease.

PLoS computational biology
Alzheimer's disease (AD) involves aggregation of amyloid β and tau, neuron loss, cognitive decline, and neuroinflammatory responses. Both resident microglia and peripheral immune cells have been associated with the immune component of AD. However, th...