AIMC Topic: Animals

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CLAW-MRM: omprehensive ipidomics utomation orkflow for ultiple eaction onitoring Using Large Language Models.

Analytical chemistry
Lipidomic profiling generates vast datasets, making manual annotation and trend interpretation complex and time-intensive. The structural and chemical diversity of the lipidome further complicates the analysis. While existing tools support targeted l...

Investigating factors influencing fatalities and injuries in animal-vehicle crashes using a random parameters logit model and ensemble machine learning approaches.

PloS one
Animal-vehicle crashes (AVC) pose risks in rural areas, often leading to casualties and injuries. Despite their infrequent occurrence, AVC can have significant consequences, especially when larger animals are involved. This study investigates factors...

Trait mediation explains decadal distributional shifts for a wide range of insect taxa.

Nature communications
Shifts in insect distributions have been reported globally, largely attributed to climate and landscape changes. Communities are being reshaped, with species response traits mediating the effects of changing environments. Using a machine-learning app...

Exploring potential associations and biomarkers linked polycystic ovarian syndrome with atherosclerosis via comprehensive bioinformatics analysis, machine learning, and animal experiments.

Functional & integrative genomics
Polycystic ovary syndrome (PCOS), a common endocrine condition affecting multiple systems, is tied to atherosclerosis (AS) progression among reproductive-aged women. The present study aimed to explore the underlying associations and uncover potential...

3D-printed chitosan-starch mesh filled with minocycline-alginate hydrogel for dual anti-Staphylococcus aureus and osteogenic effects.

Carbohydrate polymers
Bone infections, particularly those caused by Staphylococcus aureus, pose clinical challenges due to biofilm formation and association with bone loss. To address this, we developed a three-dimensional (3D) printed hydrogel-based drug delivery device ...

Predicting current habitat suitability for intermediate snail hosts of urogenital and intestinal schistosomiasis in the Lower Shire Valley floodplain of southern Malawi.

Parasites & vectors
BACKGROUND: Relating the geographical distribution of intermediate freshwater snail hosts (viz. vectors of schistosomes) to local environmental attributes offers value for understanding the epidemiological landscape of schistosomiasis transmission in...

Significant correlation between ferroptosis-associated genes and ulcerative colitis: implications for diagnosis and treatment.

European journal of medical research
BACKGROUND: Ulcerative colitis (UC) is a significant type of inflammatory bowel disease (IBD). Ferroptosis is a type of procedural death that is associated with different types of diseases to various degrees. This study aimed to explore the key ferro...

Optimized hierarchical CLSTM model for sentiment classification of tweets using boosted killer whale predation strategy.

Scientific reports
Opinion mining is more challenging than it was before because of all the user-generated material on social media. People use Twitter (X) to gather opinions on products, advancements, and laws. Sentiment Analysis (SA) examines people's thoughts, feeli...

MZB1-Driven Endoplasmic reticulum stress model as a predictor of breast cancer progression and survival.

Functional & integrative genomics
Endoplasmic reticulum (ER) stress and its associated unfolded protein response (UPR) have been demonstrated to play a crucial role in cancer's progression, but their prognostic significance in breast cancer (BC) remains unclear. In this study, a reli...

Deep learning in chromatin organization: from super-resolution microscopy to clinical applications.

Cellular and molecular life sciences : CMLS
The 3D organization of the genome plays a critical role in regulating gene expression, maintaining cellular identity, and mediating responses to environmental cues. Advances in super-resolution microscopy and genomic technologies have enabled unprece...