AIMC Topic: Animals
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Infrared thermography of beef carcasses and random forest algorithm to predict temperature and pH of Longissimus thoracis on carcasses.
Meat science
Apr 10, 2025
This study aimed to evaluate the use of infrared thermography (IRT) as a method for predicting the initial and ultimate temperature, as well as the pH, of the Longissimus thoracis in beef carcasses (LTBC). A total of 102 beef carcasses, consisting of...
μGlia-Flow, an automatic workflow for microglia segmentation and classification.
Journal of neuroscience methods
Apr 10, 2025
BACKGROUND: Microglia are important immune cells in the central nervous system, playing a key role in various pathological processes. The morphological diversity of microglia is closely linked to the development of brain diseases, yet accurate segmen...
Traditional Chinese medicine as a promising choice for future control of PEDV.
Virus research
Apr 10, 2025
Porcine epidemic diarrhea virus (PEDV) is the major agent of the recent outbreaks of diarrhea in piglets, which has caused huge economic losses to the global swine industry. Since traditional vaccine strategies cannot provide complete protection for ...
Micro- and Nano-Bots for Infection Control.
Advanced materials (Deerfield Beach, Fla.)
Apr 10, 2025
Medical micro- and nano-bots (MMBs and MNBs) have attracted a lot of attention owing to their precise motion for accessing difficult-to-reach areas in the body. These emerging tools offer the promise of non-invasive diagnostics and therapeutics for a...
An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology.
Neuron
Apr 10, 2025
Neurotechnologies and genetic tools for dissecting neural circuit functions have advanced rapidly over the past decade although the development of complementary pharmacological methodologies has comparatively lagged. Understanding the precise pharmac...
CLIC1 and IFITM2 expression in brain tissue correlates with cognitive impairment via immune dysregulation in sepsis and Alzheimer's disease.
International immunopharmacology
Apr 10, 2025
BACKGROUND: Sepsis, a life-threatening condition driven by dysregulated host responses to infection, is associated with long-term cognitive impairments resembling Alzheimer's disease (AD). However, the molecular mechanisms linking sepsis-induced cogn...
First report on Quantitative Structure-Toxicity Relationship modeling approaches for the prediction of acute toxicity of various organic chemicals against rotifer species.
The Science of the total environment
Apr 10, 2025
Nowadays, organic chemicals are crucial components in virtually every aspect of daily life, serving as indispensable elements for modern society. The ongoing synthesis of chemicals and the various potential harmful effects on living organisms are pro...
Therapeutic effect and concomitant toxicity of hydrargyrum chloratum compositum on chronic difficult-to-heal wounds in rats.
Journal of ethnopharmacology
Apr 10, 2025
ETHNOPHARMACOLOGICAL RELEVANCE: Hydrargyrum chloratum compositum(Hcc) is a traditional Chinese medicine for external use, with the efficacy of 'transforming corrosion and pulling out toxins, removing corrosion and regenerating muscles'. The main comp...
Artificial intelligence in central-peripheral interaction organ crosstalk: the future of drug discovery and clinical trials.
Pharmacological research
Apr 10, 2025
Drug discovery before the 20th century often focused on single genes, molecules, cells, or organs, failing to capture the complexity of biological systems. The emergence of protein-protein interaction network studies in 2001 marked a turning point an...
Assessing concordance between RNA-Seq and NanoString technologies in Ebola-infected nonhuman primates using machine learning.
BMC genomics
Apr 10, 2025
This study evaluates the concordance between RNA sequencing (RNA-Seq) and NanoString technologies for gene expression analysis in non-human primates (NHPs) infected with Ebola virus (EBOV). A detailed comparison of both platforms revealed a strong co...
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