AIMC Topic: Area Under Curve

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Using Data-Driven Algorithms with Large-Scale Plasma Proteomic Data to Discover Novel Biomarkers for Diagnosing Depression.

Journal of proteome research
Given recent technological advances in proteomics, it is now possible to quantify plasma proteomes in large cohorts of patients to screen for biomarkers and to guide the early diagnosis and treatment of depression. Here we used CatBoost machine learn...

Tree-based ensemble machine learning models in the prediction of acute respiratory distress syndrome following cardiac surgery: a multicenter cohort study.

Journal of translational medicine
BACKGROUND: Acute respiratory distress syndrome (ARDS) after cardiac surgery is a severe respiratory complication with high mortality and morbidity. Traditional clinical approaches may lead to under recognition of this heterogeneous syndrome, potenti...

Focal liver lesion diagnosis with deep learning and multistage CT imaging.

Nature communications
Diagnosing liver lesions is crucial for treatment choices and patient outcomes. This study develops an automatic diagnosis system for liver lesions using multiphase enhanced computed tomography (CT). A total of 4039 patients from six data centers are...

Development and validation of prediction models for nosocomial infection and prognosis in hospitalized patients with cirrhosis.

Antimicrobial resistance and infection control
BACKGROUND: Nosocomial infections (NIs) frequently occur and adversely impact prognosis for hospitalized patients with cirrhosis. This study aims to develop and validate two machine learning models for NIs and in-hospital mortality risk prediction.

Machine learning in diagnostic support in medical emergency departments.

Scientific reports
Diagnosing patients in the medical emergency department is complex and this is expected to increase in many countries due to an ageing population. In this study we investigate the feasibility of training machine learning algorithms to assist physicia...

A Machine Learning Algorithm to Predict the Starting Dose of Daptomycin.

Clinical pharmacokinetics
BACKGROUND AND OBJECTIVE: The dosage of daptomycin is usually based on body weight. However, it has been shown that this approach yields too high an exposure in obese patients. Pharmacokinetic and pharmacodynamic indexes (PK/PD) have been proposed fo...

CT-based deep learning radiomics biomarker for programmed cell death ligand 1 expression in non-small cell lung cancer.

BMC medical imaging
BACKGROUND: Programmed cell death ligand 1 (PD-L1), as a reliable predictive biomarker, plays an important role in guiding immunotherapy of lung cancer. To investigate the value of CT-based deep learning radiomics signature to predict PD-L1 expressio...

Pediatric cardiac surgery: machine learning models for postoperative complication prediction.

Journal of anesthesia
PURPOSE: Managing children undergoing cardiac surgery with cardiopulmonary bypass (CPB) presents a significant challenge for anesthesiologists. Machine Learning (ML)-assisted tools have the potential to enhance the recognition of patients at risk of ...

Enhancing identification performance of cognitive impairment high-risk based on a semi-supervised learning method.

Journal of biomedical informatics
BACKGROUND: Cognitive assessment plays a pivotal role in the early detection of cognitive impairment, particularly in the prevention and management of cognitive diseases such as Alzheimer's and Lewy body dementia. Large-scale screening relies heavily...