AIMC Topic: Automation, Laboratory
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Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Jun 19, 2018
Currently, the growing demand on quick, easy and ecological sample pretreatment methods is unquestionable. Such challenge involves also approaches focusing on the analysis of pharmaceuticals and other endogenous compounds in biological matrices, term...
Automated Preparation of MS-Sensitive Fluorescently Labeled N-Glycans with a Commercial Pipetting Robot.
SLAS technology
Apr 4, 2018
N-Glycan analysis is routinely performed for biotherapeutic protein characterization. A recently introduced N-glycan analysis kit using RapiFluor-MS (RFMS) labeling provides time savings over reductive amination labeling methods while also providing ...
Automated Interpretation of Blood Culture Gram Stains by Use of a Deep Convolutional Neural Network.
Journal of clinical microbiology
Feb 22, 2018
Microscopic interpretation of stained smears is one of the most operator-dependent and time-intensive activities in the clinical microbiology laboratory. Here, we investigated application of an automated image acquisition and convolutional neural net...
Multi-neuron intracellular recording in vivo via interacting autopatching robots.
eLife
Jan 3, 2018
The activities of groups of neurons in a circuit or brain region are important for neuronal computations that contribute to behaviors and disease states. Traditional extracellular recordings have been powerful and scalable, but much less is known abo...
Design and validation of an automated solid phase extraction liquid chromatography coupled mass spectrometry method for the quantification of propofol in plasma.
Journal of pharmaceutical and biomedical analysis
Dec 21, 2017
Propofol concentration in human plasma can be quantified by liquid chromatography coupled mass spectrometry. Sample preparation usually requires solid phase extraction to remove matrix components and enrich the analyte. To facilitate user-independent...
A European multicenter study on the analytical performance of the VERIS HBV assay.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Dec 19, 2017
BACKGROUND: Hepatitis B viral load monitoring is an essential part of managing patients with chronic Hepatits B infection. Beckman Coulter has developed the VERIS HBV Assay for use on the fully automated Beckman Coulter DxN VERIS Molecular Diagnostic...
Automated computer-based detection of encounter behaviours in groups of honeybees.
Scientific reports
Dec 15, 2017
Honeybees form societies in which thousands of members integrate their behaviours to act as a single functional unit. We have little knowledge on how the collaborative features are regulated by workers' activities because we lack methods that enable ...
Automatic Classification of Cancerous Tissue in Laserendomicroscopy Images of the Oral Cavity using Deep Learning.
Scientific reports
Sep 20, 2017
Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer of the oral epithelium. Despite their high impact on mortality, sufficient screening methods for early diagnosis of OSCC often lack accuracy and thus OSCCs are mostly diagnosed at a late ...
Automated Training of Deep Convolutional Neural Networks for Cell Segmentation.
Scientific reports
Aug 10, 2017
Deep Convolutional Neural Networks (DCNN) have recently emerged as superior for many image segmentation tasks. The DCNN performance is however heavily dependent on the availability of large amounts of problem-specific training samples. Here we show t...
A Method Based on Artificial Intelligence To Fully Automatize The Evaluation of Bovine Blastocyst Images.
Scientific reports
Aug 9, 2017
Morphological analysis is the standard method of assessing embryo quality; however, its inherent subjectivity tends to generate discrepancies among evaluators. Using genetic algorithms and artificial neural networks (ANNs), we developed a new method ...
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