Urbanization modifies the composition of dissolved organic matter (DOM) and nitrogen nutrients, profoundly affecting river microbial communities. However, the mechanisms driving pathogenic and non-pathogenic bacteria remain unclear. In this study, we...
Resistance to antimicrobial agents has become a global threat, estimated to cause 10-million deaths annually by 2050. Antimicrobial peptides are emerging as an alternative and offer advantages over traditional antibiotics. Antimicrobial peptides gene...
Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data f...
The response of aquatic animal gut microbiota to microplastics has been extensively studied and shows sensitivity, however, the potential of using gut microbiota as indicators for microplastic pollution has not yet been fully explored. To address thi...
Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder frequently accompanied by psychological symptoms. Bacterial microbiota plays a critical role in mediating local and systemic immunity, and alterations in these microbial communities...
Vitamin B is a vital nutrient for the normal functioning of many metabolic processes. It has a characteristic corrinoid ring structure with a cobalt ion. Its complex chemical structure demands 30 enzyme-catalyzed steps for synthesis. Deficiency of th...
Effluent released from municipal wastewater treatment plants reflects the microbial communities responsible for degrading and removing contaminants within the plants. Monitoring this effluent offers essential insights into its environmental impacts, ...
The hyporheic zone (HZ) of treated sewage-dominated rivers serves as a critical biogeochemical hotspot for dissolved organic nitrogen (DON) transformation, yet the mechanisms linking DON chemodiversity to microbial community dynamics remain poorly re...
Amino acids are crucial nitrogen sources in high-temperature Daqu (HTD), and they can significantly influence the quality of HTD. This study investigated amino acid patterns by analyzing fermentation parameters and microbial communities. Correlation ...
European journal of medicinal chemistry
Jun 29, 2025
Antimicrobial resistance (AMR) has emerged as one of the foremost public health threats of the 21st century. The progressive decline in the efficacy of conventional antibiotics, combined with a scarcity of new drug classes approved in recent decades,...
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