Breast Cancer (BRCA) is a heterogeneous disease, and it is one of the most prevalent cancer types among women. Developing effective treatment strategies that address diverse types of BRCA is crucial. Notably, among different BRCA molecular sub-types,...
BACKGROUND & OBJECTIVE: This study aimed to identify key immune-related biomarkers of benign schwannoma through machine learning-assisted transcriptomic and single-cell analyses, and to construct a predictive model for disease evaluation.
Gastric cancer (GC) ranks as the fifth most commonly diagnosed malignancy and the fourth leading cause of cancer-related mortality worldwide. The integration of machine learning in the analysis of GC metabolomics data for biomarker identification rem...
BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, due to lacking effective early-stage screening approaches. Imaging, such as low-dose CT, poses radiation risk, and biopsies can induce some complications. Additi...
Radiotherapy resistance in nasopharyngeal carcinoma (NPC) is a major cause of recurrence and metastasis. Identifying radiotherapy-related biomarkers is crucial for improving patient survival outcomes. This study developed the nasopharyngeal carcinoma...
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Jun 17, 2025
BACKGROUND: Gastric cancer (GC) presents challenges in predicting treatment responses due to its patient-specific heterogeneity. Recently, liquid biopsies have emerged as a valuable data modality, offering essential cellular and molecular insights wh...
Journal of cancer research and clinical oncology
Jun 17, 2025
BACKGROUND: With the improvement of imaging, the screening rate of Pulmonary nodules (PNs) has further increased, but their identification of High-Risk Prognostic Pathological Components (HRPPC) is still a major challenge. In this study, we aimed to ...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jun 16, 2025
This study focuses on artificial intelligence-driven classification of glioma and Ki-67 leveling using T2w-FLAIR MRI, exploring the association of Ki-67 biomarkers with deep learning (DL) features through explainable artificial intelligence (XAI) and...
DNA methylation is a fundamental epigenetic modification that regulates gene expression and maintains genomic stability. Consequently, DNA methylation remains a key biomarker in cancer research, playing a vital role in diagnosis, prognosis, and tailo...
Metabolomics : Official journal of the Metabolomic Society
Jun 14, 2025
INTRODUCTION: Breast cancer is the most common cancer among women, with its burden increasing over the past decades. Early diagnosis significantly improves survival rates and reduces lethality. Innovative technologies are being developed for early de...
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