Lymphoma, a clonal malignancy from lymphocytes, includes diverse subtypes requiring distinct immunohistochemical stains for accurate diagnosis. Limited biopsy specimens often restrict the use of multiple stains, complicating diagnostic workflows. Lym...
Computer methods and programs in biomedicine
Aug 1, 2025
BACKGROUND AND OBJECTIVE: Measuring the thickness of the glomerular basement membrane (GBM) and assessing the percentage of podocyte foot process effacement (%PFPE) are important for diagnosing non-neoplastic kidney diseases. However, when performed ...
Liver international : official journal of the International Association for the Study of the Liver
Jul 1, 2025
BACKGROUND AND AIMS: Liver biopsy is the gold standard for assessing fibrosis in cirrhotic livers, yet cirrhosis is spatially heterogeneous and continuously remodels. This study evaluates a novel phenotypic digital pathology platform for continuous f...
BACKGROUND: Assessing the extent of inflammation in peritubular capillaries (PTCs) is important for diagnosing antibody-mediated rejection in kidney transplant biopsies. However, this assessment is time-consuming and suffers from interobserver variab...
Archives of pathology & laboratory medicine
Jul 1, 2025
CONTEXT.—: Seegene Medical Foundation, one of the major clinical laboratories in South Korea, developed SeeDP, an artificial intelligence (AI)-based postanalytic daily quality control (QC) system that reassesses all gastrointestinal (GI) endoscopic b...
Current opinion in organ transplantation
Jun 1, 2025
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...
American journal of clinical pathology
May 17, 2025
OBJECTIVE: The highly specialized language used in prostate biopsy pathology reports coupled with low rates of health literacy leave some patients unable to comprehend their medical information. Patients' use of online search engines can lead to misi...
BACKGROUND: Basal cell carcinoma (BCC) is the most common skin cancer, placing a significant burden on healthcare systems globally. Developing high-precision automated diagnostics requires large annotated datasets, which are costly and difficult to o...
International journal of molecular sciences
May 9, 2025
Currently, the focus of intraoperative imaging in brain tumor surgery is beginning to shift to optical methods such as optical coherence tomography (OCT), Raman spectroscopy, confocal laser endomicroscopy (CLE), and fluorescence lifetime imaging (FLI...
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