AIMC Topic: Biopsy

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Identification and validation of interferon-stimulated gene 15 as a biomarker for dermatomyositis by integrated bioinformatics analysis and machine learning.

Frontiers in immunology
BACKGROUND: Dermatomyositis (DM) is an autoimmune disease that primarily affects the skin and muscles. It can lead to increased mortality, particularly when patients develop associated malignancies or experience fatal complications such as pulmonary ...

Machine Learning Models for Predicting Significant Liver Fibrosis in Patients with Severe Obesity and Nonalcoholic Fatty Liver Disease.

Obesity surgery
PURPOSE: Although noninvasive tests can be used to predict liver fibrosis, their accuracy is limited for patients with severe obesity and nonalcoholic fatty liver disease (NAFLD). We developed machine learning (ML) models to predict significant liver...

Rapid On-Site Histology of Lung and Pleural Biopsies Using Higher Harmonic Generation Microscopy and Artificial Intelligence Analysis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Lung cancer is one of the most prevalent and lethal cancers. To improve health outcomes while reducing health care burden, it becomes crucial to move toward early detection and cost-effective workflows. Currently, there is no method for the on-site r...

Artificial intelligence-based quantification of lymphocytes in feline small intestinal biopsies.

Veterinary pathology
Feline chronic enteropathy is a poorly defined condition of older cats that encompasses chronic enteritis to low-grade intestinal lymphoma. The histological evaluation of lymphocyte numbers and distribution in small intestinal biopsies is crucial for...

Self-Supervised Learning for Feature Extraction from Glomerular Images and Disease Classification with Minimal Annotations.

Journal of the American Society of Nephrology : JASN
BACKGROUND: Deep learning has great potential in digital kidney pathology. However, its effectiveness depends heavily on the availability of extensively labeled datasets, which are often limited because of the specialized knowledge and time required ...

A Deep Learning System to Predict Epithelial Dysplasia in Oral Leukoplakia.

Journal of dental research
Oral leukoplakia (OL) has an inherent disposition to develop oral cancer. OL with epithelial dysplasia (OED) is significantly likely to undergo malignant transformation; however, routine OED assessment is invasive and challenging. This study investig...

A deep learning approach to case prioritisation of colorectal biopsies.

Histopathology
AIMS: To create and validate a weakly supervised artificial intelligence (AI) model for detection of abnormal colorectal histology, including dysplasia and cancer, and prioritise biopsies according to clinical significance (severity of diagnosis).

Diagnosis of odontogenic keratocysts and non-keratocysts using edge attention convolution neural network.

Minerva dental and oral science
BACKGROUND: The study's objective was to develop an automated method for a histopathology recognition model for odontogenic keratocysts (OKC) and non-keratocyst (Non-KC) in jaw cyst sections stained with hematoxylin (H) and eosin (E) on a tiny bit of...

Diagnosis of Hirschsprung disease by analyzing acetylcholinesterase staining using artificial intelligence.

Journal of pediatric gastroenterology and nutrition
OBJECTIVES: Classical Hirschsprung disease (HD) is defined by the absence of ganglion cells in the rectosigmoid colon. The diagnosis is made from rectal biopsy, which reveals the aganglionosis and the presence of cholinergic hyperinnervation. However...