AIMC Topic: Biopsy

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Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens.

The Journal of pathology Dec 11, 2024
The presence, location, and extent of prostate cancer is assessed by pathologists using H&E-stained tissue slides. Machine learning approaches can accomplish these tasks for both biopsies and radical prostatectomies. Deep learning approaches using co...
Neural Networks, Computer Male Deep Learning Prostatic Neoplasms Humans Biopsy Prostatectomy
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Quantitative fibrosis identifies biliary tract involvement and is associated with outcomes in pediatric autoimmune liver disease.

Hepatology communications Dec 11, 2024
BACKGROUND: Children with autoimmune liver disease (AILD) may develop fibrosis-related complications necessitating a liver transplant. We hypothesize that tissue-based analysis of liver fibrosis by second harmonic generation (SHG) microscopy with art...
Cholangitis, Sclerosing Liver Transplantation Autoimmune Diseases Hepatitis, Autoimmune Young Adult Humans Child Male Artificial Intelligence Liver Cirrhosis Adolescent Prognosis Liver Child, Preschool Female Biopsy
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Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection.

Computers in biology and medicine Dec 10, 2024
BACKGROUND AND OBJECTIVES: Oral cancer is a global health challenge. The disease can be successfully treated if detected early, but the survival rate drops significantly for late stage cases. There is a growing interest in a shift from the current st...
Optical Imaging Mouth Mucosa Papanicolaou Test Early Detection of Cancer Multimodal Imaging Biopsy Mouth Neoplasms Microscopy Image Interpretation, Computer-Assisted Datasets as Topic Humans Adult Deep Learning
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Comparison of deep learning schemes in grading non-alcoholic fatty liver disease using B-mode ultrasound hepatorenal window images with liver biopsy as the gold standard.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) Dec 2, 2024
BACKGROUND/INTRODUCTION: To evaluate the performance of pre-trained deep learning schemes (DLS) in hepatic steatosis (HS) grading of Non-Alcoholic Fatty Liver Disease (NAFLD) patients, using as input B-mode US images containing right kidney (RK) cort...
Aged Adult Male Middle Aged Humans Female Non-alcoholic Fatty Liver Disease Reference Standards Image Processing, Computer-Assisted Kidney Deep Learning Liver Ultrasonography Biopsy ROC Curve
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Pediatric Liver Transplant Pathology: An Update and Practical Consideration.

Surgical pathology clinics Nov 28, 2024
This review provides a summary of the diagnostic approach to pediatric liver transplantation (LT) pathology. It emphasizes the pathologic features of T-cell-mediated rejection, the most common finding on liver allograft biopsies, and discusses other ...
Liver Graft Rejection Humans Biopsy Child Liver Transplantation
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Deep learning-accelerated T2WI of the prostate for transition zone lesion evaluation and extraprostatic extension assessment.

Scientific reports Nov 25, 2024
This bicenter retrospective analysis included 162 patients who had undergone prostate biopsy following prebiopsy MRI, excluding those with PCa identified only in the peripheral zone (PZ). DLR T2WI achieved a 69% reduction in scan time relative to TSE...
Retrospective Studies Aged Male Middle Aged Humans Prostate Deep Learning Biopsy ROC Curve Magnetic Resonance Imaging Prostatic Neoplasms
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Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis.

Nature medicine Nov 4, 2024
Metabolic dysfunction-associated steatohepatitis (MASH) is a major cause of liver-related morbidity and mortality, yet treatment options are limited. Manual scoring of liver biopsies, currently the gold standard for clinical trial enrollment and endp...
Biopsy Non-alcoholic Fatty Liver Disease Male Middle Aged Fatty Liver Liver Humans Female Artificial Intelligence Reproducibility of Results Adult
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Identification and validation of interferon-stimulated gene 15 as a biomarker for dermatomyositis by integrated bioinformatics analysis and machine learning.

Frontiers in immunology Nov 4, 2024
BACKGROUND: Dermatomyositis (DM) is an autoimmune disease that primarily affects the skin and muscles. It can lead to increased mortality, particularly when patients develop associated malignancies or experience fatal complications such as pulmonary ...
ROC Curve Gene Regulatory Networks Molecular Targeted Therapy Computational Biology Biomarkers Biopsy Ubiquitins Humans Molecular Docking Simulation Skin Machine Learning Gene Expression Profiling Dermatomyositis Cytokines Case-Control Studies Gene Expression Regulation
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[Pathology of transplanted heart rejection using artificial intelligence-based image analysis of endomyocardial biopsies].

Orvosi hetilap Nov 3, 2024
Humans Artificial Intelligence Female Male Image Processing, Computer-Assisted Graft Rejection Myocardium Biopsy Heart Transplantation
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Machine Learning Models for Predicting Significant Liver Fibrosis in Patients with Severe Obesity and Nonalcoholic Fatty Liver Disease.

Obesity surgery Oct 25, 2024
PURPOSE: Although noninvasive tests can be used to predict liver fibrosis, their accuracy is limited for patients with severe obesity and nonalcoholic fatty liver disease (NAFLD). We developed machine learning (ML) models to predict significant liver...
Liver Humans Predictive Value of Tests Machine Learning Biopsy Prospective Studies Non-alcoholic Fatty Liver Disease Female Male Adult Middle Aged Sensitivity and Specificity Liver Cirrhosis Bariatric Surgery Obesity, Morbid
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