AIMC Topic: Bone Diseases
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Exploring new drug treatment targets for immune related bone diseases using a multi omics joint analysis strategy.
Scientific reports
Mar 27, 2025
In the field of treatment and prevention of immune-related bone diseases, significant challenges persist, necessitating the urgent exploration of new and effective treatment methods. However, most existing Mendelian randomization (MR) studies are con...
Machine Learning-Driven Biomarker Discovery for Skeletal Complications in Type 1 Gaucher Disease Patients.
International journal of molecular sciences
Aug 6, 2024
Type 1 Gaucher disease (GD1) is a rare, autosomal recessive disorder caused by glucocerebrosidase deficiency. Skeletal manifestations represent one of the most debilitating and potentially irreversible complications of GD1. Although imaging studies a...
Study on the Effect of Low Calcium Dialysate on Biochemical Profile of Adynamic Bone Disease in Patients on Maintenance Hemodialysis.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Jan 17, 2024
In recent years, adynamic bone disease (ABD) has become a common skeletal lesion in adult patients with chronic kidney disease. We aimed to compare the effects of low calcium dialysate (LCD) and standard calcium dialysate of our facility [high calciu...
Recent Advances in Bioimage Analysis Methods for Detecting Skeletal Deformities in Biomedical and Aquaculture Fish Species.
Biomolecules
Dec 14, 2023
Detecting skeletal or bone-related deformities in model and aquaculture fish is vital for numerous biomedical studies. In biomedical research, model fish with bone-related disorders are potential indicators of various chemically induced toxins in the...
Artificial intelligence-based analysis of whole-body bone scintigraphy: The quest for the optimal deep learning algorithm and comparison with human observer performance.
Zeitschrift fur medizinische Physik
Mar 15, 2023
PURPOSE: Whole-body bone scintigraphy (WBS) is one of the most widely used modalities in diagnosing malignant bone diseases during the early stages. However, the procedure is time-consuming and requires vigour and experience. Moreover, interpretation...
A More Posterior Tibial Tubercle (Decreased Sagittal Tibial Tubercle-Trochlear Groove Distance) Is Significantly Associated With Patellofemoral Joint Degenerative Cartilage Change: A Deep Learning Analysis.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Dec 26, 2022
PURPOSE: To perform patellofemoral joint (PFJ) geometric measurements on knee magnetic resonance imaging scans and determine their relations with chondral lesions in a multicenter cohort using deep learning.
Application of Medical Imaging Based on Deep Learning in the Treatment of Lumbar Degenerative Diseases and Osteoporosis with Bone Cement Screws.
Computational and mathematical methods in medicine
Oct 11, 2021
OBJECTIVE: To explore the application value of magnetic resonance spectroscopy (MRS) and GSI-energy spectrum electronic computed tomography (CT) medical imaging based on the deep convolutional neural network (CNN) in the treatment of lumbar degenerat...
Bone Diseases
Image Interpretation, Computer-Assisted
Absorptiometry, Photon
Bone Cements
Magnetic Resonance Spectroscopy
Adipose Tissue
Bone Screws
Lumbar Vertebrae
Middle Aged
Osteoporosis
Deep Learning
Tomography, X-Ray Computed
Humans
Computational Biology
Female
Neural Networks, Computer
Bone Density
Adult
Male
Aged
Aged, 80 and over
Bone shadow segmentation from ultrasound data for orthopedic surgery using GAN.
International journal of computer assisted radiology and surgery
Jul 11, 2020
PURPOSE: Real-time, two (2D) and three-dimensional (3D) ultrasound (US) has been investigated as a potential alternative to fluoroscopy imaging in various surgical and non-surgical orthopedic procedures. However, low signal to noise ratio, imaging ar...
Skeleton Genetics: a comprehensive database for genes and mutations related to genetic skeletal disorders.
Database : the journal of biological databases and curation
Aug 31, 2016
Genetic skeletal disorders (GSD) involving the skeletal system arises through disturbances in the complex processes of skeletal development, growth and homeostasis and remain a diagnostic challenge because of their clinical heterogeneity and genetic ...
The performance of artificial intelligence chatbot large language models to address skeletal biology and bone health queries.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Mar 22, 2024
Artificial intelligence (AI) chatbots utilizing large language models (LLMs) have recently garnered significant interest due to their ability to generate humanlike responses to user inquiries in an interactive dialog format. While these models are be...
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