AIMC Topic: Brain

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Machine learning framework for early MRI-based Alzheimer's conversion prediction in MCI subjects.

NeuroImage
Mild cognitive impairment (MCI) is a transitional stage between age-related cognitive decline and Alzheimer's disease (AD). For the effective treatment of AD, it would be important to identify MCI patients at high risk for conversion to AD. In this s...

Predictive Models Based on Support Vector Machines: Whole-Brain versus Regional Analysis of Structural MRI in the Alzheimer's Disease.

Journal of neuroimaging : official journal of the American Society of Neuroimaging
Decision-making systems trained on structural magnetic resonance imaging data of subjects affected by the Alzheimer's disease (AD) and healthy controls (CTRL) are becoming widespread prognostic tools for subjects with mild cognitive impairment (MCI)....

Manifold regularized multitask feature learning for multimodality disease classification.

Human brain mapping
Multimodality based methods have shown great advantages in classification of Alzheimer's disease (AD) and its prodromal stage, that is, mild cognitive impairment (MCI). Recently, multitask feature selection methods are typically used for joint select...

Neural coordination can be enhanced by occasional interruption of normal firing patterns: a self-optimizing spiking neural network model.

Neural networks : the official journal of the International Neural Network Society
The state space of a conventional Hopfield network typically exhibits many different attractors of which only a small subset satisfies constraints between neurons in a globally optimal fashion. It has recently been demonstrated that combining Hebbian...

Predictors of schizophrenia spectrum disorders in early-onset first episodes of psychosis: a support vector machine model.

European child & adolescent psychiatry
Identifying early-onset schizophrenia spectrum disorders (SSD) at a very early stage remains challenging. To assess the diagnostic predictive value of multiple types of data at the emergence of early-onset first-episode psychosis (FEP), various suppo...

Diagnostic classification of specific phobia subtypes using structural MRI data: a machine-learning approach.

Journal of neural transmission (Vienna, Austria : 1996)
While neuroimaging research has advanced our knowledge about fear circuitry dysfunctions in anxiety disorders, findings based on diagnostic groups do not translate into diagnostic value for the individual patient. Machine-learning generates predictiv...

A framework for optimal kernel-based manifold embedding of medical image data.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Kernel-based dimensionality reduction is a widely used technique in medical image analysis. To fully unravel the underlying nonlinear manifold the selection of an adequate kernel function and of its free parameters is critical. In practice, however, ...

Time-frequency modulation of ERD and EEG coherence in robot-assisted hand performance.

Brain topography
A better understanding of cortical modifications related to movement preparation and execution after robot-assisted training could aid in refining rehabilitation therapy protocols for stroke patients. Electroencephalography (EEG) modifications of cor...

Decoding objects of basic categories from electroencephalographic signals using wavelet transform and support vector machines.

Brain topography
Decoding and classification of objects through task-oriented electroencephalographic (EEG) signals are the most crucial goals of recent researches conducted mainly for brain-computer interface applications. In this study we aimed to classify single-t...

Identifying Neuroimaging Markers of Motor Disability in Acute Stroke by Machine Learning Techniques.

Cerebral cortex (New York, N.Y. : 1991)
Conventional mass-univariate analyses have been previously used to test for group differences in neural signals. However, machine learning algorithms represent a multivariate decoding approach that may help to identify neuroimaging patterns associate...