AIMC Topic: Breast Neoplasms

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Triple-Action Therapy: Combining Machine Learning, Docking, and Dynamics to Combat BRCA1-Mutated Breast Cancer.

Molecular biotechnology
Breast cancer dominates women's mortality, and among other factors, mutations in the BRCA1 gene are significant risk factors. Several approaches are followed to treat the BRCA1 affected cancer patients. However, specific BRCA1 inhibitors are not avai...

Performance of Artificial Intelligence Chatbots in Answering Clinical Questions on Japanese Practical Guidelines for Implant-based Breast Reconstruction.

Aesthetic plastic surgery
BACKGROUND: Artificial intelligence (AI) chatbots, including ChatGPT-4 (GPT-4) and Grok-1 (Grok), have been shown to be potentially useful in several medical fields, but have not been examined in plastic and aesthetic surgery. The aim of this study i...

Diversity, inclusivity and traceability of mammography datasets used in development of Artificial Intelligence technologies: a systematic review.

Clinical imaging
PURPOSE: There are many radiological datasets for breast cancer, some which have supported the development of AI medical devices for breast cancer screening and image classification. This review aims to identify mammography datasets (including digiti...

Multi-scale region selection network in deep features for full-field mammogram classification.

Medical image analysis
Early diagnosis and treatment of breast cancer can effectively reduce mortality. Since mammogram is one of the most commonly used methods in the early diagnosis of breast cancer, the classification of mammogram images is an important work of computer...

Detecting Collagen by Machine Learning Improved Photoacoustic Spectral Analysis for Breast Cancer Diagnostics: Feasibility Studies With Murine Models.

Journal of biophotonics
Collagen, a key structural component of the extracellular matrix, undergoes significant remodeling during carcinogenesis. However, the important role of collagen levels in breast cancer diagnostics still lacks effective in vivo detection techniques t...

Subtype-Specific Detection in Stage Ia Breast Cancer: Integrating Raman Spectroscopy, Machine Learning, and Liquid Biopsy for Personalised Diagnostics.

Journal of biophotonics
This study explores the integration of Raman spectroscopy (RS) with machine learning for the early detection and subtyping of breast cancer using blood plasma samples. We performed detailed spectral analyses, identifying significant spectral patterns...

EfficientNet-resDDSC: A Hybrid Deep Learning Model Integrating Residual Blocks and Dilated Convolutions for Inferring Gene Causality in Single-Cell Data.

Interdisciplinary sciences, computational life sciences
Gene Regulatory Networks (GRNs) reveal complex interactions between genes in organisms, crucial for understanding the life system's operation. The rapid development of biotechnology, especially single-cell RNA sequencing (scRNA-seq), has generated a ...

Artificial intelligence for breast cancer detection and its health technology assessment: A scoping review.

Computers in biology and medicine
BACKGROUND: Recent healthcare advancements highlight the potential of Artificial Intelligence (AI) - and especially, among its subfields, Machine Learning (ML) - in enhancing Breast Cancer (BC) clinical care, leading to improved patient outcomes and ...

Using Machine Learning Models to Predict Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer.

JCO clinical cancer informatics
PURPOSE: Neoadjuvant chemotherapy (NAC) is increasingly used in breast cancer. Predictive modeling is useful in predicting pathologic complete response (pCR) to NAC. We test machine learning (ML) models to predict pCR in breast cancer and explore met...

Machine learning based anoikis signature predicts personalized treatment strategy of breast cancer.

Frontiers in immunology
BACKGROUND: Breast cancer remains a leading cause of mortality among women worldwide, emphasizing the urgent need for innovative prognostic tools to improve treatment strategies. Anoikis, a form of programmed cell death critical in preventing metasta...