AIMC Topic: Carcinoma, Non-Small-Cell Lung

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PET radiomics-based lymphovascular invasion prediction in lung cancer using multiple segmentation and multi-machine learning algorithms.

Physical and engineering sciences in medicine
The current study aimed to predict lymphovascular invasion (LVI) using multiple machine learning algorithms and multi-segmentation positron emission tomography (PET) radiomics in non-small cell lung cancer (NSCLC) patients, offering new avenues for p...

Deep learning-assisted interactive contouring of lung cancer: Impact on contouring time and consistency.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: To evaluate the impact of a deep learning (DL)-assisted interactive contouring tool on inter-observer variability and the time taken to complete tumour contouring.

Non-invasive multimodal CT deep learning biomarker to predict pathological complete response of non-small cell lung cancer following neoadjuvant immunochemotherapy: a multicenter study.

Journal for immunotherapy of cancer
OBJECTIVES: Although neoadjuvant immunochemotherapy has been widely applied in non-small cell lung cancer (NSCLC), predicting treatment response remains a challenge. We used pretreatment multimodal CT to explore deep learning-based immunochemotherapy...

Artificial Intelligence Recognition Model Using Liquid-Based Cytology Images to Discriminate Malignancy and Histological Types of Non-Small-Cell Lung Cancer.

Pathobiology : journal of immunopathology, molecular and cellular biology
INTRODUCTION: Artificial intelligence image recognition has applications in clinical practice. The purpose of this study was to develop an automated image classification model for lung cancer cytology using a deep learning convolutional neural networ...

Machine learning enabled classification of lung cancer cell lines co-cultured with fibroblasts with lightweight convolutional neural network for initial diagnosis.

Journal of biomedical science
BACKGROUND: Identification of lung cancer subtypes is critical for successful treatment in patients, especially those in advanced stages. Many advanced and personal treatments require knowledge of specific mutations, as well as up- and down-regulatio...

Efficient model-informed co-segmentation of tumors on PET/CT driven by clustering and classification information.

Computers in biology and medicine
Automatic tumor segmentation via positron emission tomography (PET) and computed tomography (CT) images plays a critical role in the prevention, diagnosis, and treatment of this disease via radiation oncology. However, segmenting these tumors is chal...

Integrating knowledge graphs into machine learning models for survival prediction and biomarker discovery in patients with non-small-cell lung cancer.

Journal of translational medicine
Accurate survival prediction for Non-Small Cell Lung Cancer (NSCLC) patients remains a significant challenge for the scientific and clinical community despite decades of advanced analytics. Addressing this challenge not only helps inform the critical...

Detecting pulmonary malignancy against benign nodules using noninvasive cell-free DNA fragmentomics assay.

ESMO open
BACKGROUND: Early screening using low-dose computed tomography (LDCT) can reduce mortality caused by non-small-cell lung cancer. However, ∼25% of the 'suspicious' pulmonary nodules identified by LDCT are later confirmed benign through resection surge...

CT-based deep learning radiomics biomarker for programmed cell death ligand 1 expression in non-small cell lung cancer.

BMC medical imaging
BACKGROUND: Programmed cell death ligand 1 (PD-L1), as a reliable predictive biomarker, plays an important role in guiding immunotherapy of lung cancer. To investigate the value of CT-based deep learning radiomics signature to predict PD-L1 expressio...

The impact of high-order features on performance of radiomics studies in CT non-small cell lung cancer.

Clinical imaging
High-order radiomic features have been shown to produce high performance models in a variety of scenarios. However, models trained without high-order features have shown similar performance, raising the question of whether high-order features are wor...