AIMC Topic: Cartilage, Articular

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Diagnosing osteoarthritis from T maps using deep learning: an analysis of the entire Osteoarthritis Initiative baseline cohort.

Osteoarthritis and cartilage Mar 21, 2019
OBJECTIVE: We aim to study to what extent conventional and deep-learning-based T relaxometry patterns are able to distinguish between knees with and without radiographic osteoarthritis (OA).
Humans Algorithms Female Aged Sensitivity and Specificity Male Middle Aged Disease Progression Severity of Illness Index Case-Control Studies Deep Learning Magnetic Resonance Imaging Pain Measurement Osteoarthritis, Knee Cartilage, Articular
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Automated segmentation of knee bone and cartilage combining statistical shape knowledge and convolutional neural networks: Data from the Osteoarthritis Initiative.

Medical image analysis Nov 17, 2018
We present a method for the automated segmentation of knee bones and cartilage from magnetic resonance imaging (MRI) that combines a priori knowledge of anatomical shape with Convolutional Neural Networks (CNNs). The proposed approach incorporates 3D...
Image Interpretation, Computer-Assisted Tibia Femur Osteoarthritis, Knee Cartilage, Articular Humans Neural Networks, Computer Imaging, Three-Dimensional Magnetic Resonance Imaging
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3D convolutional neural networks for detection and severity staging of meniscus and PFJ cartilage morphological degenerative changes in osteoarthritis and anterior cruciate ligament subjects.

Journal of magnetic resonance imaging : JMRI Oct 10, 2018
BACKGROUND: Semiquantitative assessment of MRI plays a central role in musculoskeletal research; however, in the clinical setting MRI reports often tend to be subjective and qualitative. Grading schemes utilized in research are not used because they ...
Neural Networks, Computer Retrospective Studies Female Reproducibility of Results Aged Humans Osteoarthritis, Knee Cartilage, Articular Anterior Cruciate Ligament Injuries Anterior Cruciate Ligament Severity of Illness Index Meniscus Anterior Cruciate Ligament Reconstruction ROC Curve Imaging, Three-Dimensional Adult Magnetic Resonance Imaging Sensitivity and Specificity False Positive Reactions Male Middle Aged
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Deep Learning Approach for Evaluating Knee MR Images: Achieving High Diagnostic Performance for Cartilage Lesion Detection.

Radiology Jul 31, 2018
Purpose To determine the feasibility of using a deep learning approach to detect cartilage lesions (including cartilage softening, fibrillation, fissuring, focal defects, diffuse thinning due to cartilage degeneration, and acute cartilage injury) wit...
Adolescent ROC Curve Magnetic Resonance Imaging Knee Joint Image Interpretation, Computer-Assisted Adult Male Middle Aged Deep Learning Arthralgia Cartilage Diseases Cartilage, Articular Knee Injuries Humans Retrospective Studies Female Aged Young Adult
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A Novel Method to Predict Knee Osteoarthritis Progression on MRI Using Machine Learning Methods.

IEEE transactions on nanobioscience May 24, 2018
This paper explored the hidden biomedical information from knee magnetic resonance (MR) images for osteoarthritis (OA) prediction. We have computed the cartilage damage index (CDI) information from 36 informative locations on tibiofemoral cartilage c...
Disease Progression Magnetic Resonance Imaging Image Interpretation, Computer-Assisted Osteoarthritis, Knee Cartilage, Articular Machine Learning Female Aged Male Middle Aged Humans
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Use of 2D U-Net Convolutional Neural Networks for Automated Cartilage and Meniscus Segmentation of Knee MR Imaging Data to Determine Relaxometry and Morphometry.

Radiology Mar 27, 2018
Purpose To analyze how automatic segmentation translates in accuracy and precision to morphology and relaxometry compared with manual segmentation and increases the speed and accuracy of the work flow that uses quantitative magnetic resonance (MR) im...
Humans Neural Networks, Computer Retrospective Studies Female Reproducibility of Results Aged Aged, 80 and over Young Adult Magnetic Resonance Imaging Adult Knee Joint Joint Diseases Male Cartilage, Articular Middle Aged Meniscus Adolescent Image Processing, Computer-Assisted
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Knee menisci segmentation using convolutional neural networks: data from the Osteoarthritis Initiative.

Osteoarthritis and cartilage Mar 9, 2018
OBJECTIVE: To present a novel method for automated segmentation of knee menisci from MRIs. To evaluate quantitative meniscal biomarkers for osteoarthritis (OA) estimated thereof.
Osteoarthritis, Knee Humans Cartilage, Articular Neural Networks, Computer Menisci, Tibial Female Disease Progression Male Time Factors Middle Aged Follow-Up Studies Magnetic Resonance Imaging Predictive Value of Tests
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Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society Mar 23, 2017
UNLABELLED: The purpose of this study is to evaluate the ability of a machine learning algorithm to classify in vivo magnetic resonance images (MRI) of human articular cartilage for development of osteoarthritis (OA). Sixty-eight subjects were select...
Osteoarthritis, Knee Cartilage, Articular Algorithms Middle Aged Cohort Studies Magnetic Resonance Imaging Regression Analysis Humans Machine Learning
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Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.

The Kaohsiung journal of medical sciences Dec 30, 2016
Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties. Phytochemical and pharmacological studies proved the oleanane-type saponins to be the main bi...
Plant Roots bcl-Associated Death Protein Interleukin-1beta bcl-X Protein NF-kappa B Matrix Metalloproteinase 9 bcl-2-Associated X Protein Rats, Sprague-Dawley Apoptosis Animals Caspase 3 Male Cyclooxygenase 2 Chondrocytes Anti-Inflammatory Agents, Non-Steroidal Plant Extracts Cartilage, Articular Saponins Rats Matrix Metalloproteinase 3 Tumor Suppressor Protein p53 Inflammation Primary Cell Culture Gene Expression Regulation Signal Transduction Achyranthes Proliferating Cell Nuclear Antigen
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Tenascin-C Prevents Articular Cartilage Degeneration in Murine Osteoarthritis Models.

Cartilage Dec 4, 2016
Objective The objective of this study was to determine whether intra-articular injections of tenascin-C (TNC) could prevent cartilage damage in murine models of osteoarthritis (OA). Design Fluorescently labeled TNC was injected into knee joints and i...
Collagen Type II Cartilage Diseases Cartilage, Articular Tenascin Disease Models, Animal Animals Mice, Inbred BALB C Male Knee Joint Mice Injections, Intra-Articular Synovial Membrane Osteoarthritis, Knee
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