BACKGROUND: Parkinson disease (PD) is a common neurodegenerative disease characterized by both motor and nonmotor symptoms. Cognitive impairment often occurs early in the disease and can persist throughout its progression, severely impacting patients...
American journal of Alzheimer's disease and other dementias
Mar 14, 2025
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH p...
Aging clinical and experimental research
Mar 12, 2025
BACKGROUND: Early prediction of progression in dementia is of major importance for providing patients with adequate clinical care, with considerable impact on the organization of the whole healthcare system.
BACKGROUND: Cognitive impairment and depressive symptoms are prevalent and closely interrelated mental health issues in the elderly. Traditional methods for identifying depressive symptoms in this population often lack effectiveness. Machine learning...
An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises volumetric me...
BACKGROUND: Dementia is a multifaceted disorder that affects cognitive function, necessitating accurate diagnosis for effective management and treatment. Although the Mini-Mental State Examination (MMSE) is widely used to assess cognitive impairment,...
Cognitive impairment in cerebral small vessel disease (CSVD) progresses subtly but carries significant clinical consequences, necessitating effective diagnostic tools. This study developed and validated predictive models for CSVD-related cognitive im...
International journal of molecular sciences
Mar 8, 2025
Mild cognitive impairment (MCI) is a clinical condition characterized by a decline in cognitive ability and progression of cognitive impairment. It is often considered a transitional stage between normal aging and Alzheimer's disease (AD). This study...
Alzheimer's disease (AD) is a severe neurological illness that demolishes memory and brain functioning. This disease affects an individual's capacity to work, think, and behave. The proportion of individuals suffering from AD is rapidly increasing. I...
The immersive experience provided by our approach empowers researchers with an intuitive exploration of brain structures. Within the brain's central nervous system, encompassing both white and gray matter, symptoms associated with Alzheimer's disease...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.