AIMC Topic: Coinfection
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Cases of Monkeypox show highly-overlapping co-infection with HIV and syphilis.
Frontiers in public health
Jan 5, 2024
PURPOSE: Ongoing Monkeypox (MPX) outbreaks in countries outside Africa have unique characteristics. However, data on cohorts of confirmed cases in China is limited. The study provides important epidemiological, diagnostic, and clinical information ab...
Identifying the Interaction Between Tuberculosis and SARS-CoV-2 Infections via Bioinformatics Analysis and Machine Learning.
Biochemical genetics
Nov 22, 2023
The number of patients with COVID-19 caused by severe acute respiratory syndrome coronavirus 2 is still increasing. In the case of COVID-19 and tuberculosis (TB), the presence of one disease affects the infectious status of the other. Meanwhile, coin...
Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
Nov 6, 2023
BACKGROUND: Progressive interventions have recently improved programmatic outcomes in drug-resistant tuberculosis (DR-TB) care in South Africa (SA). Amidst these, a shorter regimen was introduced in 2017 with weak evidence, and has shown mixed result...
A three-methylation-driven gene-based deep learning model for tuberculosis diagnosis in patients with and without human immunodeficiency virus co-infection.
Microbiology and immunology
May 27, 2022
Improved diagnostic tests for tuberculosis (TB) among people with human immunodeficiency virus (HIV) are urgently required. We hypothesized that methylation-driven genes (MDGs) of host blood could be used to diagnose patients co-infected with HIV/TB....
A Novel Deep Learning-Based Black Fungus Disease Identification Using Modified Hybrid Learning Methodology.
Contrast media & molecular imaging
Jan 27, 2022
Currently, countries across the world are suffering from a prominent viral infection called COVID-19. Most countries are still facing several issues due to this disease, which has resulted in several fatalities. The first COVID-19 wave caused devasta...
PACIFIC: a lightweight deep-learning classifier of SARS-CoV-2 and co-infecting RNA viruses.
Scientific reports
Feb 5, 2021
Viral co-infections occur in COVID-19 patients, potentially impacting disease progression and severity. However, there is currently no dedicated method to identify viral co-infections in patient RNA-seq data. We developed PACIFIC, a deep-learning alg...
Artificial Intelligence Applied to Gene Expression Testing (IVIGET) to Predict Trivalent Inactivated Influenza Vaccine Immunogenicity in HIV Infected Children.
Frontiers in immunology
Oct 5, 2020
The number of patients affected by chronic diseases with special vaccination needs is burgeoning. In this scenario, predictive markers of immunogenicity, as well as signatures of immune responses are typically missing even though it would especially ...
Humans
Artificial Intelligence
Coinfection
Influenza, Human
Influenza Vaccines
Influenza A Virus, H1N1 Subtype
Immunogenicity, Vaccine
Vaccines, Inactivated
Hemagglutination Inhibition Tests
Prognosis
HIV Infections
Reproducibility of Results
Child
Gene Expression Profiling
Computational Biology
Transcriptome
Vaccination
Using machine learning methods to determine a typology of patients with HIV-HCV infection to be treated with antivirals.
PloS one
Jan 10, 2020
Several European countries have established criteria for prioritising initiation of treatment in patients infected with the hepatitis C virus (HCV) by grouping patients according to clinical characteristics. Based on neural network techniques, our ob...
Intelligent Network DisRuption Analysis (INDRA): A targeted strategy for efficient interruption of hepatitis C transmissions.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
May 31, 2018
Hepatitis C virus (HCV) infection is a global public health problem. The implementation of public health interventions (PHI) to control HCV infection could effectively interrupt HCV transmission. PHI targeting high-risk populations, e.g., people who ...
UPLC-MS/MS method for the simultaneous quantification of sofosbuvir, sofosbuvir metabolite (GS-331007) and daclatasvir in plasma of HIV/HCV co-infected patients.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 12, 2017
Direct-acting antiviral agents (DAAs) represent the major advance in hepatitis C virus (HCV) infection treatment leading to extremely high eradication rates in HCV mono- and HIV/HCV co-infected patients. In this scenery, availability of Therapeutic D...
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