AIMC Topic: Colitis, Ulcerative

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Performance of a Deep Learning Model vs Human Reviewers in Grading Endoscopic Disease Severity of Patients With Ulcerative Colitis.

JAMA network open May 3, 2019
IMPORTANCE: Assessing endoscopic disease severity in ulcerative colitis (UC) is a key element in determining therapeutic response, but its use in clinical practice is limited by the requirement for experienced human reviewers.
Colitis, Ulcerative Male Video Recording Middle Aged Colonoscopy Severity of Illness Index Deep Learning Humans Retrospective Studies Female Reproducibility of Results Adult
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Novel computer-assisted diagnosis system for endoscopic disease activity in patients with ulcerative colitis.

Gastrointestinal endoscopy Oct 24, 2018
BACKGROUND AND AIMS: Evaluation of endoscopic disease activity for patients with ulcerative colitis (UC) is important when determining the treatment of choice. However, endoscopists require a certain period of training to evaluate the activity of inf...
Algorithms Female Aged Aged, 80 and over Young Adult Humans Neural Networks, Computer Adolescent ROC Curve Colitis, Ulcerative Intestinal Mucosa Area Under Curve Adult Male Middle Aged Colonoscopy Diagnosis, Computer-Assisted
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Fully automated diagnostic system with artificial intelligence using endocytoscopy to identify the presence of histologic inflammation associated with ulcerative colitis (with video).

Gastrointestinal endoscopy Sep 27, 2018
BACKGROUND AND AIMS: In the treatment of ulcerative colitis (UC), an incremental benefit of achieving histologic healing beyond that of endoscopic mucosal healing has been suggested; persistent histologic inflammation increases the risk of exacerbati...
Intestinal Mucosa Rectum Automation Female Reproducibility of Results Sensitivity and Specificity Male Middle Aged Colon Colonoscopy Diagnosis, Computer-Assisted Inflammation Colitis, Ulcerative Humans Artificial Intelligence Machine Learning Algorithms Retrospective Studies
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Inflammatory bowel disease patients experiencing a loss of response to infliximab regain long-term response after undergoing granulocyte/monocyte apheresis: A case series.

Cytokine Dec 29, 2017
Up to 50% of patients with ulcerative colitis (UC) or Crohn's disease (CD) experience a loss of response (LOR) to infliximab after an initial response to the drug. Granulocyte/monocyte apheresis (GMA) with the Adacolumn depletes the activated myeloid...
Colitis, Ulcerative C-Reactive Protein Adult Humans Infliximab Interleukin-6 Leukapheresis Male Prospective Studies Middle Aged Female Time Factors Interleukin-17
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Infliximab trough levels and persistent vs transient antibodies measured early after induction predict long-term clinical remission in patients with inflammatory bowel disease.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Nov 27, 2017
BACKGROUND: The use of therapeutic drug monitoring has been proposed as a useful tool in the management of patients with loss of response to biological therapy in patients with inflammatory bowel disease.
Drug Monitoring Antibodies Infliximab Crohn Disease Gastrointestinal Agents Male Middle Aged Humans Time Factors ROC Curve Prospective Studies Colitis, Ulcerative Remission Induction Female Drug Resistance Aged Young Adult Adult
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Serum Interleukin-33 level in Saudi children with inflammatory bowel disease.

International journal of clinical and experimental pathology Dec 1, 2015
Interleukin-33 (IL-33) is a cytokine that belongs to the interleukin-1 family and has been shown to be associated with mucosal inflammation. The aim of this study was to determine the serum level of IL-33 in children with ulcerative colitis (UC) and ...
C-Reactive Protein Crohn Disease Inflammation Mediators Up-Regulation Nephelometry and Turbidimetry Interleukin-33 Prognosis Female Cross-Sectional Studies Age Factors Male Humans Biological Products Severity of Illness Index Prospective Studies Colitis, Ulcerative Biomarkers Diagnosis, Differential Predictive Value of Tests Case-Control Studies Saudi Arabia Adolescent Child Enzyme-Linked Immunosorbent Assay
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Seasonal variation in onset and relapse of IBD and a model to predict the frequency of onset, relapse, and severity of IBD based on artificial neural network.

International journal of colorectal disease May 15, 2015
BACKGROUND: Previous research has yielded conflicting data as to whether the natural history of inflammatory bowel disease follows a seasonal pattern. The purpose of this study was (1) to determine whether the frequency of onset and relapse of inflam...
Colitis, Ulcerative Crohn Disease Weather Humans Seasons Neural Networks, Computer Recurrence Forecasting Female Adult Male Middle Aged Severity of Illness Index Incidence
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Explainable artificial intelligence for prediction of refractory ulcerative colitis: analysis of a Japanese Nationwide Registry.

Annals of medicine Dec 1, 2025
OBJECTIVE: Ulcerative colitis (UC) is a chronic inflammatory bowel disease for which remission is dependent on corticosteroid (CS) treatment. The diversity of disease pathophysiology necessitates optimal case-specific treatment selection. This study ...
Humans Artificial Intelligence Machine Learning Prognosis Adrenal Cortex Hormones Middle Aged Female Aged Young Adult Adult Male Colitis, Ulcerative Registries Remission Induction Japan
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Vedolizumab in inflammatory bowel disease: Real-world outcomes and their prediction with machine learning-the IG-IBD LIVE study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Jul 1, 2025
BACKGROUND AND AIMS: Real-world studies on vedolizumab in inflammatory bowel disease (IBD) are often limited by small sample size and short follow-up. In this study, we investigated the 2-year effectiveness and safety of vedolizumab in patients with ...
Crohn Disease Gastrointestinal Agents Remission Induction Middle Aged Treatment Outcome Antibodies, Monoclonal, Humanized Colitis, Ulcerative Italy Humans Machine Learning Inflammatory Bowel Diseases Female Aged Young Adult Adult Male
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Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis.

Inflammatory bowel diseases Jun 13, 2025
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by increased stool frequency, rectal bleeding, and urgency. To streamline the quantitative assessment of histopathology using the Nancy Index in UC patients, we...
Humans Neural Networks, Computer Middle Aged Severity of Illness Index Deep Learning Colitis, Ulcerative Proof of Concept Study Artificial Intelligence Female Young Adult Adult Male
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