AIMC Topic: Colonic Neoplasms

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A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells.

Nature communications
DNA replication stress is a hallmark of cancer that is exploited by chemotherapies. Current assays for replication stress have low throughput and poor resolution whilst being unable to map the movement of replication forks genome-wide. We present a n...

Multi-module UNet++ for colon cancer histopathological image segmentation.

Scientific reports
In the pathological diagnosis of colorectal cancer, the precise segmentation of glandular and cellular contours serves as the fundamental basis for achieving accurate clinical diagnosis. However, this task presents significant challenges due to compl...

Establishment of two pathomic-based machine learning models to predict CLCA1 expression in colon adenocarcinoma.

PloS one
Chloride channel accessory 1 (CLCA1) is considered a potential prognostic biomarker for colon adenocarcinoma (COAD). The objective of this research was to develop two pathomics models to predict CLCA1 expression from hematoxylin-eosin (H&E) stained p...

ColoViT: a synergistic integration of EfficientNet and vision transformers for advanced colon cancer detection.

Journal of cancer research and clinical oncology
BACKGROUND: Colon cancer remains a leading cause of cancer-related mortality globally, highlighting the urgent need for advanced diagnostic methods to improve early detection and patient outcomes.

An enhanced fusion of transfer learning models with optimization based clinical diagnosis of lung and colon cancer using biomedical imaging.

Scientific reports
Lung and colon cancers (LCC) are among the foremost reasons for human death and disease. Early analysis of this disorder contains various tests, namely ultrasound (US), magnetic resonance imaging (MRI), and computed tomography (CT). Despite analytica...

Establishment of a machine learning-based predictive model with dual-center external validation: investigating the role of robotic surgery in preventing delayed gastric emptying for right-sided colon cancer.

Journal of robotic surgery
After colorectal surgery, delayed gastric emptying (DGE) is a clinically significant postoperative complication that significantly lowers patients' quality of life. The evolving application of robotic surgery in gastrointestinal oncology continues to...

Deep learning neural network prediction of postoperative complications in patients undergoing laparoscopic right hemicolectomy with or without CME and CVL for colon cancer: insights from SICE (Società Italiana di Chirurgia Endoscopica) CoDIG data.

Techniques in coloproctology
BACKGROUND: Postoperative complications in colorectal surgery can significantly impact patient outcomes and healthcare costs. Accurate prediction of these complications enables targeted perioperative management, improving patient safety and optimizin...

Revealing 3D microanatomical structures of unlabeled thick cancer tissues using holotomography and virtual H&E staining.

Nature communications
In histopathology, acquiring subcellular-level three-dimensional (3D) tissue structures efficiently and without damaging the tissues during serial sectioning and staining remains a formidable challenge. We address this by integrating holotomography w...

Analyzing factors influencing hospitalization costs for five common cancers in China using neural network models.

Journal of medical economics
BACKGROUND: Malignant tumors are a major global health crisis, causing 25% of deaths in China, with lung, liver, thyroid, breast, and colon cancers being the most common. Understanding the factors influencing hospitalization costs for these cancers i...

A Novel Natural Language Processing Tool Improves Colonoscopy Auditing of Adenoma and Serrated Polyp Detection Rates.

Journal of gastroenterology and hepatology
BACKGROUND AND STUDY AIMS: Determining adenoma detection rate (ADR) and serrated polyp detection rate (SDR) can be challenging as they usually involve manual matching of colonoscopy and histology reports. This study aimed to validate a Natural Langua...