AIMC Topic:
Computer Simulation

Clear Filters Showing 2191 to 2200 of 3855 articles

Minimizing postprandial hypoglycemia in Type 1 diabetes patients using multiple insulin injections and capillary blood glucose self-monitoring with machine learning techniques.

Computer methods and programs in biomedicine Jun 27, 2019
BACKGROUND: Diabetic patients treated with intensive insulin therapies require a tight glycemic control and may benefit from advanced tools to predict blood glucose (BG) concentration levels and hypo/hyperglycemia events. Prediction systems using mac...
Blood Glucose Self-Monitoring False Positive Reactions Normal Distribution Insulin Infusion Systems Bayes Theorem Hypoglycemia Postprandial Period Blood Glucose Adult Computer Simulation Capillaries Insulin Retrospective Studies Sensitivity and Specificity Diabetes Mellitus, Type 1 Male Middle Aged Female Hypoglycemic Agents Humans Reproducibility of Results Machine Learning Algorithms
View on PubMed DOI

HPO2Vec+: Leveraging heterogeneous knowledge resources to enrich node embeddings for the Human Phenotype Ontology.

Journal of biomedical informatics Jun 27, 2019
BACKGROUND: In precision medicine, deep phenotyping is defined as the precise and comprehensive analysis of phenotypic abnormalities, aiming to acquire a better understanding of the natural history of a disease and its genotype-phenotype associations...
Databases, Genetic Models, Statistical Area Under Curve Medical Informatics Semantics Biological Ontologies Rare Diseases Humans Precision Medicine Machine Learning Electronic Health Records ROC Curve Algorithms Genetic Association Studies Phenotype Computer Simulation
View on PubMed DOI

Using machine learning to characterize heart failure across the scales.

Biomechanics and modeling in mechanobiology Jun 25, 2019
Heart failure is a progressive chronic condition in which the heart undergoes detrimental changes in structure and function across multiple scales in time and space. Multiscale models of cardiac growth can provide a patient-specific window into the p...
Muscle Cells Elasticity Systole Diastole Myocardium Machine Learning Models, Cardiovascular Computer Simulation Heart Ventricles Female Heart Failure Animals Male Swine Time Factors
View on PubMed DOI

A diversity of interneurons and Hebbian plasticity facilitate rapid compressible learning in the hippocampus.

Nature neuroscience Jun 24, 2019
The hippocampus is able to rapidly learn incoming information, even if that information is only observed once. Furthermore, this information can be replayed in a compressed format in either forward or reverse modes during sharp wave-ripples (SPW-Rs)....
Interneurons Septal Nuclei Neural Networks, Computer Computer Simulation Learning Time Factors Neuronal Plasticity Memory CA3 Region, Hippocampal
View on PubMed DOI

Single-Particle Diffusion Characterization by Deep Learning.

Biophysical journal Jun 22, 2019
Diffusion plays a crucial role in many biological processes including signaling, cellular organization, transport mechanisms, and more. Direct observation of molecular movement by single-particle-tracking experiments has contributed to a growing body...
Diffusion Single Molecule Imaging Computer Simulation Deep Learning Models, Biological
View on PubMed DOI

Estimation of the radiation dose in pregnancy: an automated patient-specific model using convolutional neural networks.

European radiology Jun 21, 2019
OBJECTIVES: The conceptus dose during diagnostic imaging procedures for pregnant patients raises health concerns owing to the high radiosensitivity of the developing embryo/fetus. The aim of this work is to develop a methodology for automated constru...
Neural Networks, Computer Computer Simulation Tomography, X-Ray Computed Pregnancy Humans Radiation Dosage Monte Carlo Method Phantoms, Imaging Radiometry Female Young Adult Adult Middle Aged Radiography, Abdominal
View on PubMed DOI

Short-term synaptic plasticity expands the operational range of long-term synaptic changes in neural networks.

Neural networks : the official journal of the International Neural Network Society Jun 18, 2019
The brain is highly plastic, with synaptic weights changing across a wide range of time scales, from hundreds of milliseconds to days. Changes occurring at different temporal scales are believed to serve different purposes, with long-term changes for...
Humans Memory Neural Networks, Computer Learning Brain Time Factors Computer Simulation Neuronal Plasticity Synapses
View on PubMed DOI

DeepConv-DTI: Prediction of drug-target interactions via deep learning with convolution on protein sequences.

PLoS computational biology Jun 14, 2019
Identification of drug-target interactions (DTIs) plays a key role in drug discovery. The high cost and labor-intensive nature of in vitro and in vivo experiments have highlighted the importance of in silico-based DTI prediction approaches. In severa...
Amino Acid Sequence Ligands Deep Learning Binding Sites Computational Biology Computer Simulation Sequence Analysis, Protein Proteins Drug Discovery Models, Molecular
View on PubMed DOI

fastJT: An R package for robust and efficient feature selection for machine learning and genome-wide association studies.

BMC bioinformatics Jun 13, 2019
BACKGROUND: Parametric feature selection methods for machine learning and association studies based on genetic data are not robust with respect to outliers or influential observations. While rank-based, distribution-free statistics offer a robust alt...
Polymorphism, Single Nucleotide Blood Proteins Quantitative Trait, Heritable Machine Learning Algorithms Computer Simulation Genome-Wide Association Study
View on PubMed DOI

Enabling machine learning in X-ray-based procedures via realistic simulation of image formation.

International journal of computer assisted radiology and surgery Jun 11, 2019
PURPOSE: Machine learning-based approaches now outperform competing methods in most disciplines relevant to diagnostic radiology. Image-guided procedures, however, have not yet benefited substantially from the advent of deep learning, in particular b...
Neural Networks, Computer Machine Learning Cadaver Algorithms Scattering, Radiation Humans Tomography, X-Ray Computed Computer Simulation X-Rays Imaging, Three-Dimensional Models, Anatomic Image Processing, Computer-Assisted Fluoroscopy
View on PubMed DOI
Popular Topics
Recent Journals