AIMC Topic: Computer Simulation

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FMLNCSIM: fuzzy measure-based lncRNA functional similarity calculation model.

Oncotarget
Accumulating experimental studies have indicated the influence of lncRNAs on various critical biological processes as well as disease development and progression. Calculating lncRNA functional similarity is of high value in inferring lncRNA functions...

Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development.

Drug metabolism and disposition: the biological fate of chemicals
It is generally acknowledged that there is a need and role for informative pharmacokinetic models to improve predictions and simulation as well as individualization of drug therapy in pediatric populations of different ages and developmental stages. ...

[Study on Prediction Model of Soft Tissue Deformation during Needle Insertion].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Polyvinyl alcohol(PVA)hydrogel was made for simulating human’s soft tissue in our experiment.The image acquisition device is composed of an optical platform,a camera and its bracket and a light source.In order to study the law of soft tissue deformat...

Image reconstruction from few-view CT data by gradient-domain dictionary learning.

Journal of X-ray science and technology
BACKGROUND: Decreasing the number of projections is an effective way to reduce the radiation dose exposed to patients in medical computed tomography (CT) imaging. However, incomplete projection data for CT reconstruction will result in artifacts and ...

Storing Sequences in Binary Tournament-Based Neural Networks.

IEEE transactions on neural networks and learning systems
An extension to a recently introduced architecture of clique-based neural networks is presented. This extension makes it possible to store sequences with high efficiency. To obtain this property, network connections are provided with orientation and ...

Synaptic Mechanisms of Memory Consolidation during Sleep Slow Oscillations.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Sleep is critical for regulation of synaptic efficacy, memories, and learning. However, the underlying mechanisms of how sleep rhythms contribute to consolidating memories acquired during wakefulness remain unclear. Here we studied the ro...

Homeostatic Activity-Dependent Tuning of Recurrent Networks for Robust Propagation of Activity.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Developing neuronal networks display spontaneous bursts of action potentials that are necessary for circuit organization and tuning. While spontaneous activity has been shown to instruct map formation in sensory circuits, it is unknown wh...

A cardiac electrical activity model based on a cellular automata system in comparison with neural network model.

Pakistan journal of pharmaceutical sciences
Cardiac Electrical Activity is commonly distributed into three dimensions of Cardiac Tissue (Myocardium) and evolves with duration of time. The indicator of heart diseases can occur randomly at any time of a day. Heart rate, conduction and each elect...

Objective prediction of pharyngeal swallow dysfunction in dysphagia through artificial neural network modeling.

Neurogastroenterology and motility
BACKGROUND: Pharyngeal pressure-flow analysis (PFA) of high resolution impedance-manometry (HRIM) with calculation of the swallow risk index (SRI) can quantify swallow dysfunction predisposing to aspiration. We explored the potential use of artificia...